RSS:Mastadon

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[1]

(RSS) (Biomed Chrom) LC–MS/MS and GC–MS Analysis‐Based Novel Bioactive Compounds From Endophyte Acremonium sclerotigenum CBS 124.42 Isolated From Stevia rebaudiana (Bertoni) Bertoni: ABSTRACT

Endophytes are microorganisms that reside inside the living tissues of leaves and possess antimicrobial, antioxidant, anticancer and anti-inflammatory activity etc. Liquid chromatography–tandem mass spectrometry (LC–MS/MS) represents a powerful… analyticalsciencejournals.onli

2025-12-16 21:12:14
[2]

(RSS) (BioRxiv All) Molecular profiling of glioblastoma-derived extracellular vesicles identifies small nucleolar RNAs as candidate liquid biomarkers for radiation-induced senescence: Radiation-induced senescence (RIS) in glioblastoma (GBM) is an undesirable cell fate that inhibits tumor cell death and supports resistance and outgrowth. While senescence-targeting drugs are promising adjuvants, their clinical application will require proper patient… biorxiv.org/content/10.64898/2...

2025-12-16 19:45:10
[3]

(RSS) (ABioanChem) Development and optimization of PFAS extraction in soil’s headspace followed by multidimensional gas chromatography and mass spectrometry: Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic “forever chemicals” due to their exceptional stability resulting from the strong carbon-fluorine bond, which makes them persistent, bioaccumulative, and associated with health and ecological risks. Despite their relatively high… link.springer.com/ar...

2025-12-16 19:11:37
[4]

(RSS) (ABioanChem) Development of a GC-MS/MS method to quantify 120 gut microbiota-derived metabolites: The gut microbiota produces metabolites that are important for host physiology and have critical roles in the development of diseases, such as metabolic disorders, cardiovascular diseases, and cancer. Here, we developed a gas chromatography-coupled tandem mass spectrometry (GC-MS/MS) method for the quantification of 120 volatile and semi-volatile compounds… link.springer.com/artic...

2025-12-16 18:02:16
[5]

(RSS) (ABioanChem) Analysis and fate of per- and polyfluoroalkyl substances (PFAS) in the global aquatic environment: perspectives and combined risks with microplastics: Per- and polyfluoroalkyl substances (PFAS) are synthetic, highly persistent environmental contaminants increasingly recognized for their global occurrence, bioaccumulation potential, and toxicological impacts. This review provides a critical overview of analytical challenges and the… link.springer.com/article/10.1

2025-12-16 17:10:07
[6]

(RSS) (ABioanChem) Evaluating the chemical safety of bio-based and biodegradable food packaging materials through non-targeted LC-HRMS analysis and in vitro bioassays: Bio-based and/or biodegradable polymers like all food-contact materials shall not transfer their constituents to food in quantities which could endanger human health. This work aims to evaluate the chemical safety of food contact bioplastics through an approach that combines a non-targeted… link.springer.com/article/1...

2025-12-16 16:20:36
[7]

(RSS) (ChemRxiv) Separation of Sulfated Fucose-containing Isomers found in L.digitata using Cyclic Ion Mobility Mass Spectrometry: Brown seaweeds and some marine invertebrates contain bioactive polysaccharides including fucoidan. These biopolymers have antimicrobial, antibacterial, and antifungal properties, and improved characterization of their structures would be valuable as it can correlated with their bioactivity. To our knowledge,… dx.doi.org/10.26434/chemrxiv-2

2025-12-16 11:05:36
[8]

(RSS) (BioRxiv All) Mass Spectrometric Determination of Site-Specific O-Acetylation in Rhamnogalacturonan-I Oligomers: O-Acetylation, a common modification in rhamnogalacturonan I (RG-I), is critical for various biological processes, including plant growth, stress responses, and pathogen defense. Precise determination of the degree and specific positions of acetylation is therefore essential. To date, nuclear magnetic resonance (NMR) and tandem mass… biorxiv.org/content/10.64898...

2025-12-16 05:51:31
[9]

(RSS) (JASMS) [ASAP] Implementation of Infrared-Activated Negative Electron Transfer Dissociation (IR-NETD) Using Xenon on a Quadrupole-Orbitrap-Quadrupole Linear Ion Trap Mass Spectrometer: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00345 dx.doi.org/10.1021/jasms.5c003 (RSS)

2025-12-15 22:22:35
[10]

(RSS) (JASMS) [ASAP] Improving Peak Capacity in Glycan Ion Mobility Separations through Traveling Wave-Based Ion Heating: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00323 dx.doi.org/10.1021/jasms.5c003 (RSS)

2025-12-15 21:11:33
[11]

(RSS) (JASMS) [ASAP] IscS Kinetics in Native Mass Spectrometry Buffers Reveal Key Physiochemical Properties that Influence Enzyme Activity: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00280 dx.doi.org/10.1021/jasms.5c002 (RSS)

2025-12-15 19:44:34
[12]

(RSS) (MS Reviews) Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research: Abstract

Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to… analyticalsciencejournals.onli

2025-12-15 19:12:15
[13]

(RSS) (BioRxiv All) TOE1 influences canonical Wnt signalling in myeloid leukaemia cells through LEF-1 modulation and regulates the proliferation of haematopoietic cells through PAK2.: Acute myeloid leukaemia (AML) is an aggressive haematological malignancy characterised by the clonal proliferation of myeloid progenitor cells in the bone marrow and peripheral blood. Dysregulation of the Wnt/{beta}-catenin pathway has been implicated in the… biorxiv.org/content/10.64898/2

2025-12-15 18:02:09
[14]

(RSS) (ABioanChem) Evaluating chromatographic techniques for the aroma profiling of kombucha: Kombucha is a fermented beverage made from the addition of a symbiotic community of bacteria and yeast (SCOBY) to a sugary base tea. Despite the odors associated with kombucha, few studies have examined its chemical aroma profile. The mixture of volatile organic compounds (VOCs) from tea and its fermentation is typically examined using one-dimensional gas… link.springer.com/article/10.1

2025-12-15 16:21:16
[15]

(RSS) (ChemRxiv) Comparative Analysis of Conventional Cell Lysis Techniques to Electrochemical Cell Lysis using the Liquid Microjunction Surface Sampling Probe: Cell lysis is a critical step in the analysis of cellular components, influencing the efficiency, reproducibility, and integrity of biomolecular extractions. Conventional lysis techniques, including mechanical and chemical methods, often present trade-offs between throughput,… dx.doi.org/10.26434/chemrxiv-2

2025-12-15 11:05:34
[16]

(RSS) (BioRxiv All) Uncovering the link between ATP synthase and the TCA cycle by crosslinking mass spectrometry: Mitochondrial oxidative phosphorylation (OXPHOS) comprises a series of multi-subunit protein complexes that operate in coordination with the tricarboxylic acid (TCA) cycle to generate ATP. Although these systems are metabolically interconnected, complex II is generally regarded as the only direct structural link between the OXPHOS and… biorxiv.org/content/10.64898/2

2025-12-15 03:15:33
[17]

(RSS) (Proteom Res News) From LCMS to clinical diagnostics! Is proteomics finally realizing potential? A new win!:  

I'd have went with the MCP abstract graphic but it's all smooshed up on my screen.

Related, we just had Mike MacCoss on The Proteomics Show (dude won the Don Hunt award for distinguished contribution in proteomics!). I try to always ask guests what they're most excited about in the present/future of proteomics and he… proteomicsnews.blogspot.com/20

2025-12-14 21:11:35
[18]

(RSS) De novo sequencing of glycans by ion mobility-mass spectrometry using a self-expanding database nature.com/articles/s41467-025

2025-12-14 07:49:32
[19]

(RSS) (BioRxiv All) Gene replacement therapy for Piga GPI-anchor deficiency in the developing nervous system: Glycosylphosphatidylinositol (GPI) anchors are a class of post-translational modifications observed on over 150 proteins. Pathogenic variants in the GPI biosynthesis enzyme, PIGA, in humans are associated with several brain anomalies such as hypomyelination, cerebellar hypoplasia, ataxic gait, and can lead to premature mortality. We… biorxiv.org/content/10.64898/2

2025-12-14 03:16:08
[20]

(RSS) (JASMS) [ASAP] Separation of Epimers of a Cleavable ADC Drug Linker Using SLIM–Ion Mobility Mass Spectrometry: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00270 dx.doi.org/10.1021/jasms.5c002 (RSS)

2025-12-13 21:11:34
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