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[1]

(RSS) A versatile toolkit for drug metabolism studies with GNPS2: from drug development to clinical monitoring nature.com/articles/s41596-025

2025-09-09 02:15:35
[2]

(RSS) (J An Atom Spec) Single Particle ICP-TOFMS for the detection of micro-scale polystyrene and polyvinyl chloride from artificially aged bulk plastic: J. Anal. At. Spectrom., 2025, Accepted Manuscript
DOI: 10.1039/D5JA00213C, Technical Note Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Raquel Gonzalez de Vega, Maximilian Huber, Isabel S. Jüngling, Natalia Ivleva, David Clases
A… pubs.rsc.org/en/Content/Articl

2025-09-08 22:39:33
[3]

(RSS) (BioRxiv All) TurboID proximity interactome mapping reveals NR2E3 association with AP-1 and retinal developmental complexes: The photoreceptor-specific nuclear receptor NR2E3 is a key transcription factor in the retinal transcriptional network, essential in photoreceptor cell fate and maintenance. Various biallelic loss-of-function variants lead to autosomal recessive inherited retinal disease (IRD), while a single missense variant G56R has… biorxiv.org/content/10.1101/20

2025-09-08 21:22:33
[4]

(RSS) (J Ag Food Chem) [ASAP] Mapping Royal Jelly’s Bioactive Profile by Liquid Chromatography Coupled to Trapped Ion Mobility Spectrometry and High-Resolution Mass Spectrometry: Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.5c04904 dx.doi.org/10.1021/acs.jafc.5c

2025-09-08 20:11:35
[5]

(RSS) (BioRxiv All) Accumulation of ibuprofen in endemic amphipods of Lake Baikal: Pharmaceutical pollutants, including ibuprofen, are now ubiquitously detected in global aquatic ecosystems, exerting significant negative ecological impacts. Lake Baikal organisms have been documented to accumulate ibuprofen and related contaminants. This study quantified ibuprofen concentrations within Lake Baikal's endemic amphipod fauna using high-performance… biorxiv.org/content/10.1101/20

2025-09-08 18:44:33
[6]

(RSS) (JASMS) [ASAP] Algorithm-Driven Chromatographic Method for Prostaglandin Isomer Identification via Tandem Mass Spectrometry: Journal of the American Society for Mass SpectrometryDOI: 10.1021/jasms.5c00231 dx.doi.org/10.1021/jasms.5c002 (RSS)

2025-09-08 17:02:06
[7]

RSS Feed: (Analyst) Production process defects of MiXi beverage detected by neutral desorption extractive electrospray ionization mass spectrometry: Analyst, 2025, 150,4070-4080
DOI: 10.1039/D5AN00299K, PaperLingling Pan, Manman Qin, Leting Wang, Lu Huang, Huiyu Xing, Ning Wang, Tongtong Yang, Liyun Hu, Rui Su, Huanwen Chen
ND-EESI-MS enables online detection of chemical fingerprints of Mixi beverage. Process defects were traced via… pubs.rsc.org/en/Content/Articl

2025-09-08 16:23:33
[8]

(RSS) (RCM) An Optimized Method for Extraction and Detection of Polycyclic Aromatic Hydrocarbons in Soil/Sediment—Based on Gas Chromatography–Tandem Mass Spectrometry: Rapid Communications in Mass Spectrometry, Volume 39, Issue 24, 30 December 2025. analyticalsciencejournals.onli

2025-09-08 13:03:37
[9]

(RSS) (BioRxiv All) Top-Down Individual Ion Mass Spectrometry Reveals 85-110 kDa Catenin Phospho-Proteoforms Regulated by Actomyosin Contractility: A central challenge in top-down proteomics is the characterization of large proteoforms (>70 kDa) due to their high spectral complexity in mass spectrometers. Here, we advance individual ion mass spectrometry (I2MS) for intact mass and fragmentation analysis of - and {beta}-catenins (85-110 kDa), key… biorxiv.org/content/10.1101/20

2025-09-08 03:47:32
[10]

(RSS) (BioRxiv All) Peptide-RNA photo-crosslinks with tunable RNA chain map protein-RNA interfaces: Photo-crosslinking mass spectrometry enables the identification of protein-RNA interactions in living cells, pinpointing interaction interfaces at single-amino acid resolution. However, current isolation procedures for peptide-RNA crosslinks eliminate the RNA moiety, prohibiting sequencing of the RNA alongside the crosslinked peptide. Here, we… biorxiv.org/content/10.1101/20

2025-09-08 01:17:33
[11]

(RSS) (IJMS) GC-MS unveils monosaccharide D-Allose in Terminalia arjuna bark extract acting against biofilm regulatory proteins (SrtA and SarA) of Staphylococcus aureus: A drug discovery approach: Publication date: Available online 6 September 2025

Source: International Journal of Mass Spectrometry

Author(s): Shraavani Konatam, Dijendra Nath Roy sciencedirect.com/science/arti

2025-09-08 00:05:32
[12]

(RSS) (BioRxiv All) Deciphering the mechanistic basis for the pathological effect of the Gαo E246K mutation in neurodevelopmental disorder: Mutations in the GNAO1 gene, which encodes for Go, a major neuronal G protein, are associated with neurodevelopmental disorders, epilepsy, and movement disorders. We identified and characterized a spontaneous heterozygous GNAO1 E246K mutation in an Israeli female infant with complex developmental delays and… biorxiv.org/content/10.1101/20

2025-09-07 20:12:09
[13]

(RSS) (Proteom Res News) Finally the paper to convince you to toss that nanoLC off a roof?:  

If you've ever been to this blog  before, you might have encountered the fact that I despite nanoflow liquid chromatography. 

These authors seem to agree! 

I rarely quote the text of a paper completely, but I'm going to do it with this great new one. 

Begin quote: 

When I started my first proteomics experiment in 2007 or something, I… proteomicsnews.blogspot.com/20

2025-09-07 18:44:33
[14]

(RSS) (BioRxiv All) Erucamide regulates retinal neurovascular crosstalk: Neurovasculoglial crosstalk is critical in establishing and maintaining a functional neurovascular unit. Breakdown in the unit is central to many neurodegenerative disorders of the CNS of which the retina is a component. A growing literature indicated that primary fatty acid amides (PFAMs) can regulate this crosstalk between vasculature and neuronal tissues. In this study we… biorxiv.org/content/10.1101/20

2025-09-07 18:11:33
[15]

(RSS) (BioRxiv All) Proteome-wide impact of LRRK1 and 2 inhibitors on protein interactions and phosphorylation: The Leucine-rich repeat kinases 1 and 2 (LRRK1 and 2) are large, multidomain proteins and closely related members of the Roco protein family. They share a high similarity in domain structure and are both phosphorylate members of the Rab GTPase family. However, while mutations to LRRK1 are only implicated in rare cases of osteopetrosis,… biorxiv.org/content/10.1101/20

2025-09-07 17:01:09
[16]

(RSS) (ACS Anal Chem) [ASAP] Chemical Tagging with Mass Spectrometry Analysis for Sensitive Determination of Carboxylic Enantiomers in Hepatic Fibrosis: Analytical ChemistryDOI: 10.1021/acs.analchem.5c03449 dx.doi.org/10.1021/acs.analche

2025-09-07 16:09:33
[17]

(RSS) (BioRxiv All) Changes in Histone Isoform Abundance and Histone Post-Translational Modifications during Anoxia Tolerance and Recovery in WS40NE cells of Austrofundulus limnaeus: Anoxia is an often-lethal stressor to vertebrates, yet some vertebrates have adapted cellular mechanisms to survive in anoxic conditions. Embryos of the annual killifish Austrofundulus limnaeus have the greatest tolerance to anoxia of all vertebrates, yet the epigenetic… biorxiv.org/content/10.1101/...

2025-09-07 04:51:32
[18]

(RSS) (BioRxiv All) In Situ, Antibody-Independent, and Multiplexed Characterization of Amyloid Plaques by MALDI MS/MS Imaging Using iprm-PASEF: Background Amyloidosis describes a heterogeneous group of diseases caused by the extracellular deposition of misfolded proteins, affecting one or multiple organs and eventually leading to organ failure. Identification of the amyloidogenic protein leading to the correct subtyping is challenging but crucial… biorxiv.org/content/10.1101/20

2025-09-07 03:48:08
[19]

(RSS) (BioRxiv All) Increasing Applicability of Automated mD-LC-MS Peptide Mapping for Biopharmaceuticals via Streamlined In-Solution Digestion: Since the introduction of the first multidimensional liquid chromatography mass spectrometry (mD-LC-MS) approach for antibody peak characterization, multiple developments have been reported including integration of various chromatographic approaches and precise fractionation, providing high quality and… biorxiv.org/content/10.1101/20

2025-09-07 03:28:32
[20]

(RSS) (J Chrom A) Open-source liquid chromatography-mass spectrometry data processing tools for RNA modification analysis: Publication date: Available online 6 September 2025

Source: Journal of Chromatography A

Author(s): Jiawei Wang, Zhenwei Jiang, Zihui Jin, Ziqiang Cao, Pan Deng sciencedirect.com/science/arti

2025-09-07 02:15:32
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