RSS:Analytical Chemistry

Analytical Chemistry

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[ASAP] Dual-Mode Chalcone-Based Fluorescent Probe for Distinguishing Amyloid-β Oligomers and Fibrils via Microenvironment Sensitivity

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04779

— Zhe Zhou, Zi-Xin Chen, Yi-Ting Zeng, Chaiqin Shi, Wen-Lin Tang, Li-Wen Zhang, You Cheng, Yuexing Zhang, Pan Wu, and Hang-Xing Wang 2025-10-30 09:36:19

[ASAP] Time-Resolved Phosphorescence and Colorimetric Assays of Diabetes Biomarkers: Simultaneous Detection of 3-Nitro-l-Tyrosine and Total Antioxidant Capacity via Zeolite-Confined Carbon Dots

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05306

— Huifang Wu, Qiqi Wang, Lingfeng Zhu, Xinyue Liu, Lizhong Liu, and Changlun Tong 2025-10-30 19:19:48

[ASAP] Engineered Exosomes Disguised NIR-II Nanoaggregates for High-Resolution Photoacoustic Angiography and Robust Photothermal Therapy of Glioblastoma

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05448

— Yang Bai, Chuangli Zhang, Ziyong Wu, Jing He, Xinya Zhao, Anyu Zhang, Pengfei Shi, and Shusheng Zhang 2025-10-30 12:50:49

[ASAP] Characterizing Mixed Polyethylene Glycol Monolayers with Surface-Bound Ferrocene for Label-Free Immunosensing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03527

— Emie Marin, Brandaise Martinez, Tessa Whitaker, Emily N. Gallichotte, Gregory D. Ebel, Yann R. Leroux, Philippe Hapiot, and Charles S. Henry 2025-10-29 09:54:20

[ASAP] Visible and Long-Lasting Chemiluminescence System for Dual Colorimetric and Chemiluminescent Humidity Monitoring

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03694

— Qiang Cheng, E. Pang, Yuanyu Tang, Yating Xu, Baili Yang, Shaojing Zhao, Benhua Wang, Xiangzhi Song, Yi Zhang, and Minhuan Lan 2025-10-29 19:13:13

[ASAP] Investigation on Droplet Heat Transfer Characteristics of Continuous-Flow PCR

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04157

— Jiyu Meng, He Zhang, Xiaotong Sun, Chengzhuang Yu, Xinhang Feng, Chunyang Wei, Changbin Yu, and Shanshan Li 2025-10-29 12:10:22

[ASAP] Postcolumn Infusion of Labeled Racemic Chiral Selector Enables LC-Chiral MS/MS

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04406

— Xingcheng Gong, Yang Yang, Lijuan Wu, Jiahui Wen, Zihan Zhu, Ke Zhang, Haiyu Zhao, Liang Zhang, Pengfei Tu, and Yuelin Song 2025-10-29 18:57:44

[ASAP] Shear Stress-Induced Microstructure Remodeling of Human Bicuspid Aortopathy Revealed by Nonlinear Optical Microscopy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04657

— Lili Zhang, Yuntao Lu, Wencong Hong, Shuo Cong, Jiaying Li, Huan Liu, Chunsheng Wang, Lai Wei, Jianpeng Ao, Wenshuo Wang, and Minbiao Ji 2025-10-29 14:44:46

[ASAP] Construction of a Bifunctional Single-Quantum Dot Nanosensor for Enzyme-Free Detection of N6-Methyladenosine Demethylase in Breast Cancer

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04759

— Meng Liu, Wen Zhang, Chen-chen Li, Dandan Zhang, Ning-ning Zhao, and Chun-yang Zhang 2025-10-29 15:01:35

[ASAP] A Chimeric Photo-Controllable CRISPR/Cas12a System for Universal and Fast Diagnostics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04782

— Xinrong Yan, Bin Liu, Shuguang Zhou, Yanjun Fan, Shijiong Wei, Dehui Qiu, Henglong Xiang, Jiahang Zhou, Jean-Louis Mergny, David Monchaud, Huangxian Ju, and Jun Zhou 2025-10-29 16:03:11

[ASAP] Electrochemiluminescence Resonance Energy Transfer Biosensor Based on Self-Enhanced Terbium-Based Metal–Organic Frameworks with Antenna Effect for Sensitive MicroRNA-155 Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04977

— Ruiyan Liu, Zhuoxin Ye, Yongli Wu, Yan Zhang, Mo Ma, Pinyi Ma, and Daqian Song 2025-10-29 09:03:42

[ASAP] Logic-Gated Surface-Enhanced Raman Scattering Nanoplatform for Dual-Amplified Cancer Cell Imaging and Targeted Photothermal Ablation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05156

— Zhichao Xia, Jiayi Zeng, Junjian Lu, Chen Wang, Xing-Hua Xia, and Jin Wang 2025-10-29 16:12:48

[ASAP] A Novel Perovkite Nanocrystals-Based Photochromic Fluorescent Sensor for Facile, Selective, Sensitive, and Visualized Detection of 3,3′-Dichlorobenzidine and for Implicit Application to Real-Time and Visualized Monitoring of Pollutant Photocatalytic Degradation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05218

— Zheyang Chi, Yuan Qin, Jingcheng Zheng, Yuwu Chi, Shulin Zhao, and Fanggui Ye 2025-10-29 17:44:55

[ASAP] Defect-Involved Chemiluminescence of Unary Copper Nanocrystals towards Semi-Automatic Immunoassay

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05245

— Xiaoxuan Ren, Yue Sun, Shengjie Li, Xuwen Gao, and Guizheng Zou 2025-10-29 18:21:26

[ASAP] Laser Secondary Neutral Mass Spectrometry of Bi3+ Sputtered Pharmaceuticals

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05459

— Michael Bäumer, Richard E. Peterson, Heinrich F. Arlinghaus, and Bonnie J. Tyler 2025-10-29 17:06:40

[ASAP] Electrochemical Quantification of Lithium Oxide Impurity in Lithium Sulfide via Lithium–Sulfur Battery Operation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05780

— Yun Ho Jeong, Garam Chung, Gwan Hyeon Park, Byoung Ju Kim, Won Bae Kim, and Changshin Jo 2025-10-29 12:46:48

[ASAP] Aerith: Visualization and Annotation of Isotopic Enrichment Patterns of Peptides and Metabolites with Stable Isotope Labeling from Proteomics and Metabolomics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03207

— Yi Xiong, Ryan S. Mueller, Shichao Feng, Xuan Guo, and Chongle Pan 2025-10-28 13:51:43

[ASAP] Breaking the Size Barrier: SERS-Based Ultrasensitive Detection and Quantification of Polystyrene Plastics in Real Water Samples

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03318

— Ao Wang, Qianqian Ding, Jiahao Mou, Hongbin Qi, Jiazhi Yang, Urol K. Makhmanov, A. V. Rogachev, and Xiaohong Jiang 2025-10-28 11:51:24

[ASAP] Disposable Carbon Screen-Printed Electrodes for On-Chip Protein Digestion: A Proteomic Approach Coupled to MALDI-TOF MS

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03760

— Lucas F. Castro, Fanny d’Orlyé, Joelle Vinh, Yann Verdier, and Anne Varenne 2025-10-28 15:31:39

[ASAP] Microplastic Mass Estimation Using Two-Dimensional Chemical Images from Quantum-Cascade Laser-Based Infrared Spectrometers

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04003

— Borja Ferreiro, José M. Andrade, Adrián López-Rosales, and Soledad Muniategui-Lorenzo 2025-10-28 18:33:37

[ASAP] Lasso Peptide Syanodin I: Loop-Pulling Two-Step Thermal Unthreading Mechanism

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04118

— Miguel Santos-Fernandez, Kevin Jeanne Dit Fouque, Ukesh Karki, Alain Blond, Séverine Zirah, Prem P. Chapagain, Julian D. Hegemann, and Francisco Fernandez-Lima 2025-10-28 14:44:06

[ASAP] Transition Metal Dichalcogenide-Based Heterojunction Band Alignment-Enabled Organic Photoelectrochemical Transistor Biosensing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04325

— Feng-Zao Chen, Lin Zhang, Yuan Gao, Lu Hou, Song-Peng Xu, Bing Sun, and De-Man Han 2025-10-28 11:22:56

[ASAP] The Cu Nanocluster-Sensitized and Filter-Concentrated Strategy for Rapid and Ultrasensitive Naked-Eyed Colorimetric Detection of Pathogens

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04358

— Wei Yang, Wenbo Jiang, Qiming Huang, Tianchi Leng, Leyi Zhang, Yaxin Zhang, Shan Chen, Yuanqing Gao, and Yimin Fang 2025-10-28 18:10:46

[ASAP] Sunlight-Driven Potassium Ion-Intercalated Nanozyme for Efficient Photofuel Cell Construction and Environmental Pollutant Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04544

— Aijiao Guo, Bingyu Du, Qichen Chen, Ziwei Zhang, Ye Feng, and Meichuan Liu 2025-10-28 17:14:41

[ASAP] Is Digital Drying an Effective Method for Infrared Spectroscopy of Gaseous Biofluid?

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04584

— Kiran Sankar Maiti, Juergen Hauer, and Susmita Roy 2025-10-28 13:52:52

[ASAP] Adaptive Modeling of Tandem Mass Spectrometry Data: Creation of the METLIN 960K MRM Database

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04639

— Aries Aisporna, Bill Webb, Winnie Uritboonthai, Linh Hoang, Elizabeth M. Billings, Corey Hoang, Robert Plumb, and Gary Siuzdak 2025-10-28 17:16:19

[ASAP] Sericin as a New Coreactant for Lucigenin Chemiluminescence: A Novel System for the Ultrasensitive Detection of Sericin and Superoxide Dismutase

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04780

— Muhammad Saqib, Wen-Xin Chen, Yun Lei, and Ai-Lin Liu 2025-10-28 13:02:17

[ASAP] MSInet: A Self-Supervised CNN Framework Integrating Global and Local Context for Robust Mass Spectrometry Imaging Segmentation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04885

— Mudassir Shah, Siyang Liu, Lei Guo, Yusong Zhang, Lingli Deng, Xiangnan Xu, Zhaodong Fei, Jingjing Xu, and Jiyang Dong 2025-10-28 15:30:39

[ASAP] Bifunctional Fluorescent Probe for Simultaneous Imaging of H2S and Hcy Crosstalk and Therapeutic Evaluation in Acute Kidney Injury

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05219

— Ting Yu, Zhengze Long, Yang Li, Yu Wu, Xin Jiang, Haoyu Jin, Han Tang, Danqing Xu, Youyu Zhang, Haitao Li, Peng Yin, and Shouzhuo Yao 2025-10-28 14:47:09

[ASAP] prm-PASEF-Based Quantification and Isomeric Model for Extended Coverage of Human Plasma Lipidome in Parkinson’s Disease

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02340

— Dhanwin Baker, Gabriel Gonzalez Escamilla, Daniel Janitschke, Yvan Devaux, Nils Schröter, Sergiu Groppa, and Laura Bindila 2025-10-27 14:09:16

[ASAP] AI-SNPS2: A Multi-Layered LC-MS/MS Platform Integrating Molecular Networking and Retention Time Prediction for Identifying Controlled and New Psychoactive Substances

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02830

— So Yeon Lee, Jihyun Lee, Jaewoo Song, Minhye Lee, Hang-Ji Ok, Eunyoung Han, Youngmin Hong, and Han Bin Oh 2025-10-27 13:25:06

[ASAP] A Detergent-Free Grinding Sample Preparation Method Dramatically Enhances PELSA for Mapping Integral Membrane Proteins–Ligand Interaction

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03099

— Ting Yu, Yan Wang, Yanan Li, Keyun Wang, Haiyang Zhu, and Mingliang Ye 2025-10-27 09:47:43

[ASAP] A CRISPR-Cas12a Fluorescent Aptasensor for Point-of-Care Drug Concentration Detection: A Synergistic Regulation by DNA Aptamer and RNA Blocker

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03744

— Chen Huang, Ling-Jie Guo, Jia-Yi Li, Yue-Wen Chen, Bing Wu, Yi-Wei Liu, Chen-Zhi Zhang, Wei-Wei Lin, Ye Yang, Jin-Yuan Chen, and Zhou-Jie Liu 2025-10-27 18:50:28

[ASAP] Posthandling Spectral Information Enhancement for Single Cell Raman Molecular Mapping Analysis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03915

— Ankit Raj, Nungnit Wattanavichean, Makoto Kawamukai, Tatsuyuki Yamamoto, and Hiro-o Hamaguchi 2025-10-27 19:00:00

[ASAP] Controllable Methylene Blue Release/Enrichment System for Ultrasensitive Electrochemical Detection of α-Fetoprotein

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03925

— Cong-Lin Zhao, Hongkai Wang, Xiaoyan Wang, Ye Zhu, and Bin Cai 2025-10-27 14:53:16

[ASAP] Activity-Triggered Chemiluminescent Probe for α-L-Fucosidase Detection from In Vitro to In Vivo

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04001

— Leisheng Xu, En Liang, Liyi Tan, Tao Che, Siying Zhi, and Kui Cheng 2025-10-27 18:42:47

[ASAP] Comprehensive Internal Standards for Hydrogen–Deuterium Exchange Mass Spectrometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05191

— Taylor Murphree, Clint Vorauer, Mason Saunders, and Miklos Guttman 2025-10-27 19:20:34

[ASAP] Nanoconfinement Synergistic Self-Catalytic Coenhanced Electrochemiluminescence Sensors for Chloramphenicol Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05369

— Jiangle Yi, Xue Dong, Yuanling Sun, Xueying Wang, Xuan Kuang, Yu Du, Hongmin Ma, Dawei Fan, Rui Feng, and Qin Wei 2025-10-27 08:52:44

[ASAP] Real-Time Binding Kinetics of Membrane Protein–Protein Interactions in a Membraneless Setting

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05510

— Yazheng Wang, Yalun Wu, Lauren A. Mayse, Danny Capucilli, Po-Jung J. Huang, Sekar Ramachandran, Soching Luikham, Jeung-Hoi Ha, Stewart N. Loh, Aaron J. Wolfe, and Liviu Movileanu 2025-10-27 12:52:09

[ASAP] Multiplex Aptamer-Guided DNA Nanosuppressors for Quantitative Modulation of Autophagy–Survivin Crosstalk and Imaging-Guided Apoptosis Induction

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05754

— Zijie Tang, Lina Zhu, Jiani Ding, Zhi-Ling Song, and Xiliang Luo 2025-10-27 18:53:31

[ASAP] Engineered Nanobodies-Based Sandwich-Competitive Immunoassay Broadens the Detection Range for Aflatoxin B1

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05346

— Wenxin Xie, Jian Chen, Jinheng Fu, Zhui Tu, Luying Duan, Wuying Yang, Xuetao Hu, Qinghua He, Wenjun Wang, and Dan Wang 2025-10-26 16:40:20

[ASAP] Probing the Formation of Metal–Organic Cages by Electrochemiluminescence

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05429

— Haijiao Peng, Yaze Chen, Ke Shi, Kun Li, Ruidong Chen, Yuhao Liu, and Chao Lu 2025-10-26 16:41:10

[ASAP] Enzymatic Self-Immobilization Enhances Chemiluminescence for Selective Tumor Imaging and Image-Guided Surgery

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04148

— Ming Liu, Zhecheng Ma, Yu Wang, Li Wu, Zhiyuan Tian, and Jian-Hong Tang 2025-10-25 12:54:41

[ASAP] A Novel Ultralow-Consumption Technique for Mafic Rock Major and Trace Element Analysis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04248

— Wan-Feng Zhang, Jia-Cheng Wu, Jun-Jie Wang, Le Zhang, Yi-Gang Xu, Yan-Qiang Zhang, Peng-Li He, De-Wen Zheng, Fei Su, Huai-Yu He, Ming Xiao, Ying-De Jiang, Fang-Fang Huang, Jiang-Ze Wang, Yong-Hua Cao, and Lin-Li Chen 2025-10-25 15:51:42

[ASAP] High-Frequency Microfluidic Fractionation for Compound-Resolved Bioactivity-Based Metabolomics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04612

— Christian Geibel, Julian Schubert, Simon B. Knoblauch, Albert Hernandez, Leonardo Boldt, Dana C. Schneider, Stilianos Papadopoulos Lambidis, Giovanni Andrea Vitale, Jakub Fleischer, Manuela Haussmann, Harald Gross, Mingxun Wang, Heike Brötz-Oesterhelt, and Daniel Petras 2025-10-25 18:57:48

[ASAP] Toward-Automated Etalon Artifacts Elimination in Dual-Wavelength Raman Spectroscopy for In Vivo Applications

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c00747

— Wenyi Xu, Renzhe Bi, Yi Qi, Ruochong Zhang, Poongkulali Rajarahm, Alicia Ann May Yap, Dinish U.S., Qian Cheng, Steven Thng, and Malini Olivo 2025-10-24 15:16:56

[ASAP] Modified Fully Automated Dried Blood Spot Sample Preparation System and Its Application in Steroid Ester Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03014

— Jing Jing, Bing Liu, Jingjing Zhao, Peijie Chen, and Xin Xu 2025-10-24 11:27:33

[ASAP] The Hyphenation of High-Performance Liquid Chromatography with X-ray Fluorescence for Universal, Flow-Through, Elemental Analysis of Organobromines

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03394

— Gaëlle Spileers, Pieter Tack, Laszlo Vincze, and Frédéric Lynen 2025-10-24 18:37:17

[ASAP] Nanochemical Cell-Surface Evaluation in Photothermal Spectroscopic Imaging of Antimicrobial Interactions in the Model System Bacillus subtilis and Vancomycin

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03502

— Maryam Ali, Robin Schneider, Anika Strecker, Nila Krishnakumar, Sebastian Unger, Mohammad Soltaninezhad, Johanna Kirchhoff, Astrid Tannert, Katerina A. Dragounova, Rainer Heintzmann, Anne-Dorothea Müller, Christoph Krafft, Ute Neugebauer, and Daniela Täuber 2025-10-24 17:00:13

[ASAP] Rambutan-Like Magnetic Nanozyme Modified with Wheat Germ Agglutinin Enhances Lateral Flow Immunoassay for Ultrasensitive and Broad-Spectrum Detection of Respiratory Microorganisms

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03762

— Yun Liu, Ting Wu, Lei Ren, Qian Wang, Zishan Xu, Guohui Sun, Bing Gu, and Chongwen Wang 2025-10-24 08:44:09

[ASAP] Etiology-Agnostic Diagnosis of Early Myocardial Ischemia via AI-Driven Label-Free Spectral Histopathology

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04142

— Tian Tian, Xudong Zhang, Ji Zhang, Kaifei Deng, Chengtao Li, Suhua Zhang, Jianhua Zhang, Junhong Sun, and Ping Huang 2025-10-24 15:54:58

[ASAP] Investigating a Systematic and Widespread Misidentification in the Metabolic Profiling Literature: Phenylacetylglutamine and Phenylacetylglycine Signal Misassignment in Proton NMR Spectra of Human and Rodent Urine

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04630

— Samuele Sala, Andres Bernal, Andres Castillo Robles, Philipp Nitschke, Reika Masuda, Janonna Kadyrov, Joram M. Posma, Paul Elliott, John C. Lindon, Ian D. Wilson, Elaine Holmes, Julien Wist, and Jeremy K. Nicholson 2025-10-24 11:28:17

[ASAP] Multicolor Biosensors for Early Diagnosis of Diseases

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04693

— Sara Aghili, Nikzad Abbariki, Hossein Daneshgar, Mohammad Edrisi, and Navid Rabiee 2025-10-24 15:19:11

[ASAP] ROS and Caspase-3 Dual-Activated Photoacoustic Probe for Enhanced Imaging of Myocardial Ischemia-Reperfusion Injury

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05680

— Penghao Zhen, Xianbao Sun, Ya Hu, Fuchao Yu, Xuan Xu, Qin Wei, Qiaochu Jiang, Xiaoyang Liu, Gaolin Liang, and Jiayi Tong 2025-10-24 15:33:46

[ASAP] Quantitative Mass Spectrometry Imaging of Amino Acids Enabled by Pyridinium Salt MALDI Probe

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c01847

— Hao Zhou, Jie Yuan, Jianfeng Xu, Yang Wang, Jiayi Ye, Shuxian Wang, Zhenhua Wan, Weihao Pei, Ying Peng, Yang Ye, Kai Wang, Jia Liu, and Jiang Zheng 2025-10-23 17:10:23

[ASAP] MXene@ZnIn2S4 Two-Dimensional Heterostructure with Enriched Sulfur Vacancies for Resonant-Gravimetric Detection of Triethylamine at ppb Level

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02605

— Ding Wang, Yuecheng Tian, Jie Guo, Ruijie Qin, Jinwu Hu, Sancan Han, Jingcheng Xu, and Qiaobo Liao 2025-10-23 14:38:55

[ASAP] Quantifying RNA Degradation with Single-Molecule Nanopore Sensing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03019

— Max K. Earle, Mohammed Alawami, Raluca-Elena Alexii, Simon Brauburger, Ulrich F. Keyser, and Casey M. Platnich 2025-10-23 19:00:00

[ASAP] Programmable Fluorescent RNA with a Catalytic Hairpin Assembly System Enables Label-Free Monitoring of MicroRNA in Living Cells

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04052

— Jun Yang, Ming-Li Su, Wei-Guo Yang, Rui-Wen Wang, Rui Jin, Jia-Min Qin, Ruo Yuan, Ying Zhuo, Ping Li, and Wen-Bin Liang 2025-10-23 15:13:19

[ASAP] Fe and Ni Dual-Atom Catalysts as High-Efficiency Coreaction Accelerators to Enhance the Electrochemiluminescence of the Carbon Dots/S2O82– System for Assessing the Acute Myocardial Infarction Protein Marker

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04625

— Jiayi Jin, Xiaochun Zhu, Pan Zhou, Haijiao Xie, Xin Peng, Yaqin Chai, and Ruo Yuan 2025-10-23 16:43:07

[ASAP] Photoresponsive HOF-Based Platforms for Large Language Model-Assisted Multimodal Diagnosis of Metabolic Diseases

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04807

— Zishuo Zhang and Bing Yan 2025-10-23 19:19:44

[ASAP] Channel-Splitting Photoassisted Enzyme Biofuel Cells: A High-Confluent and Self-Powered Platform for Electrochemistry–Photoelectrochemistry-Coupled Ratiometric Bioassays

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04991

— Cui Wang, Yang Lei, Zhuo Xing, Qihan Sun, Xuefei Zhang, Rong-Bin Song, and Zhaohui Li 2025-10-23 12:29:32

[ASAP] Ag+/Hg2+-Controlled Programmable DNA Nanostructures Enable Tumor Liquid Biopsy by Mass Spectrometry Simultaneous Sensing of Multiple Circulating Tumor DNAs

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05543

— Wanqian Lai, Xinyuan Huang, Xin Zhao, Xuemei Song, Yiman Wu, Yue Wang, Ke Huang, and Piaopiao Chen 2025-10-23 13:23:05

[ASAP] Long-Term Super-Resolution Imaging through Torsional Angle Inversed Rhodamines

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c00849

— Xue Zhang, Ying Zheng, Lujia Yang, Zhiwei Ye, and Yi Xiao 2025-10-22 15:34:56

[ASAP] GlycoFASP: A Universal Method to Prepare Complex Mixtures for O-Glycoproteomic Analysis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02666

— Shane M. Finn, Keira E. Mahoney, Taryn M. Lucas, Valentina Rangel-Angarita, Ryan J. Chen, and Stacy A. Malaker 2025-10-22 17:18:58

[ASAP] Fabricating Four-Element Doped Carbon Dots-Based Fluorescent Ratiometric Reporter Platform for CRISPR/Cas-Driven Precise Sensing of Nucleic Acids

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03228

— Muhammad Sohail, Shuyao Ma, Barira Mushtaq, Muhammad Usman Haider, Bingzhi Li, Xing Zhang, and He Huang 2025-10-22 11:00:34

[ASAP] Multiplexed Fiber-Optic Fluorescence for Functional Monitoring of Perfused Hearts

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03270

— Jianrong Qiu, Edward Waters, Emily Lupton, Friedrich Baark, Antoine L. D. Wallabregue, Stuart J. Conway, Richard Southworth, and Mads S. Bergholt 2025-10-22 12:40:54

[ASAP] An Ultrasensitive and Robust CircRNA Nanobiosensor via Magnetic Control Depuration and Catalytic Hairpin Assembly Cascade Amplification for Clinically Accessible Liquid Biopsy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03434

— Chunhan Li, Yuanhang Wei, Xinwei Li, Peng Jiang, Xuran Dong, Qunqun Guo, Qingguo Xu, Xiyue Cao, Jianfei Xia, and Zonghua Wang 2025-10-22 14:37:07

[ASAP] Macromolecular Separations by Ion Mobility Focusing in Divergent Asymmetric Electric Fields

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03506

— Hayden A. Thurman, Adetayo S. Afolayan, Atena Tajaddodi, and Alexandre A. Shvartsburg 2025-10-22 12:31:33

[ASAP] SERS-Based AND Logic Gate for Monitoring Signal Transduction of Specific Cancer Cells and Evaluating Antitumor Efficacy via Imaging of Membrane Protein Dimerization

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03545

— Xiaoyuhao Jin, Chen Dong, Tingxiao Wang, Jingjing Zhang, Jian Liu, Xiyu He, Lianhui Wang, and Chunyuan Song 2025-10-22 15:36:25

[ASAP] Toward an Event-Based and Quality-Assured Air Sampling: A Portable System for Sensing and Sampling Volatile Organic Compounds

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03799

— Thomas Mayer, Tobias Goblirsch, Ralf Petrich, and Helko Borsdorf 2025-10-22 15:54:59

[ASAP] Dopamine-Modulated Highly Oxygen-Vacancy Ce Metal–Organic Frameworks Boost Phosphatase-Catalyzed Chemiluminescence

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04138

— Hongwei Yuan, Haolin Lu, Wan Wei, Xin Jiang, Wenwen Wang, Zhifeng Fu, Guankui Long, and Hui Ouyang 2025-10-22 15:55:33

[ASAP] Characterization of Burned Soil Organic Matter via Sequential Solvent Extractions and 21 T FT-ICR Mass Spectrometry with Electrospray and Atmospheric Pressure Photoionization

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04154

— Holly K. Roth, Amy M. McKenna, Martha L. Aguilera, Jacob P. VanderRoest, Huan Chen, and Thomas Borch 2025-10-22 10:27:25

[ASAP] Performance Enhancement of SERS-Based Lateral Flow Assays: Progress and Prospective

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04694

— Zhoumi Liu, Hao Jiang, Xuefei Lv, Shuai Lian, and Xiaoqiong Li 2025-10-22 11:26:53

[ASAP] MnO2@Mn3O4 Heterojunction as a Coreactant Catalyst Collaborated with T-Shaped DNA Cycling–CRISPR/Cas12a Cascade Amplification for Locus-Specific N6-Methyladenosine RNA Modification Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04791

— Fuye Su, Heng Zhang, Chunjia Ren, Yang Jiang, Yanxia Qiao, Shengtao Zhang, Jin Liu, Sijia Li, and Yan Li 2025-10-22 16:21:06

[ASAP] Ultrasensitive Multiplexed Detection of Protein Biomarkers via Aptamer-Driven T7 RNA Polymerase Amplification

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04805

— Yongjun Li, Zixin Yang, Jiahao Wu, Liye Chen, Qian Zhao, and Haowen Huang 2025-10-22 15:35:25

[ASAP] Environmental Health Risk Assessment of Dynamic Lipid Metabolism in PCB-118-Induced Insulin Resistance Models Using a Polarity-Ultrasensitive Fluorescent Probe

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04918

— Hongshuai Zhang, Jiayi You, Jinwei Liu, Renfeng Jiang, Yuanyuan Wang, Lu Tang, Xuefeng Yang, Longwei He, and Dan Cheng 2025-10-22 08:33:22

[ASAP] AI-Enhanced Lateral Flow Assay Enables 3-Minute Quantitative Detection with Laboratory-Grade Accuracy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05108

— Jinpei Du, Chaoyu Cao, Zhenrui Xue, Weiying Wang, Xueting Lu, Yi Wei, Jingwen Huang, Lei Zhao, Lin Wang, Feng Xu, Chunyan Yao, Ting Wen, and Minli You 2025-10-22 19:45:11

[ASAP] From Static Scaffolds to Dynamic Highways: Spatially Ordered Nanotube Tracks Improve Pathway Control and Accelerate DNA Walker Kinetics for Enhanced MicroRNA Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05240

— Yongli Wu, Xin Chang, Zhuoxin Ye, Ruixin Liu, Yan Zhang, Ruiyan Liu, Pinyi Ma, and Daqian Song 2025-10-22 19:44:30

[ASAP] Predicting the Ionization Behavior of Drugs in Tissue in MALDI and MALDI-2 Mass Spectrometry Imaging Using Machine Learning

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03250

— Krischan Koerfer, Jonas Oldopp, Klaus Dreisewerd, Andrew Palmer, Jens Soltwisch, and Peter Marshall 2025-10-21 18:39:57

[ASAP] A Practical Approach for Validation of Compound Identification in Comprehensive Two-Dimensional Gas Chromatography–Mass Spectrometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04590

— Friscilla Hermatasia, Apitchaya Sanchai, Nuttanee Tungkijanansin, Phichaphop Raqsaboon, Puttaruksa Varanusupakul, Sornkanok Vimolmangkang, Ploy N. Pratanwanich, and Chadin Kulsing 2025-10-21 13:50:13

[ASAP] Highly Sensitive and Quantitative Detection of microRNA-21 in Cells Using Bipedal DNA Walker-Based Ratiometric Fluorescent Sensor

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04705

— Wenting Wei, Han Lin, Kuniharu Ijiro, and Hideyuki Mitomo 2025-10-21 13:12:44

[ASAP] Stable Converter-Powered Cascade Amplification of DNAzyme and Cas12a for Electrochemiluminescent Detection of DNA Adenine Methyltransferase

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05122

— Zhen Wang, Mei-Ling Zhao, Lu Yan, Yan-Mei Lei, Jie Liu, and Ying Zhuo 2025-10-21 08:22:13

[ASAP] Determination of Fe(II) and Fe(III) in Paramagnetic Matrices Using NMR Relaxometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02587

— Kaixu Jin, Caipeng Xu, Yufen Zhao, and Songsen Fu 2025-10-20 15:02:53

[ASAP] Online Integration of Paper Centrifugation with SERS for Sulfanilamide Antibiotic Detections in Complex Samples: Mitigating Competitive Adsorption Interference

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03222

— Shu Li, Tong Wang, Shu Ding, Xinyuan Guo, Yadi Liu, Shou-Qing Ni, Jing Chen, and Jinhua Zhan 2025-10-20 15:53:06

[ASAP] Stable and Contamination-Resistant Ag/Ag2O Micro-Reference Electrode for Alkaline Scanning Electrochemical Cell Microscopy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03484

— Jiangmei Yuan, Xiaoqing Chu, Wenfu Liu, Jiaxin Feng, Jincan Pei, Shu Chen, Canjun Liu, Jie Zhang, and Zhangquan Peng 2025-10-20 12:32:42

[ASAP] Research on the Mechanism of Enhancing the Adsorption Capacity of Molecularly Imprinted Polymers Based on the Molecular Crowding Effect

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03729

— Yue Wang, Chengli Xie, Yike Huang, Kai Zhou, and Zhining Xia 2025-10-20 13:29:57

[ASAP] Centipede-Mimetic DNA Nanomachines with Circular Sensing Modules for Spatial Monitoring of Extracellular Metabolites

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04270

— Zhenzhen Guo, Huimin Xue, Yang Wang, Yue Qiu, Peiru Chen, Jiali Zhang, Mengyu Huang, Fangmei Zhang, Qiuxia Yang, and Kaixiang Zhang 2025-10-20 15:44:09

[ASAP] Construction of a Core–Satellite Immunoassay with Homogeneous Magnet-Assisted Ratiometric Fluorescence for Highly Sensitive and Visual Detection of Inflammatory Factors

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04601

— Binbin Wang, Yuning Zhang, Jie Li, Yanbing Lv, Li Wang, Yangchao Shi, Ning Li, Ruili Wu, Huaibin Shen, and Lin Song Li 2025-10-20 17:46:07

[ASAP] Engineering a Metal–Organic Framework-Dominated Bioinspired Multienzymatic Sensor Array for Portable Detection of Perfluoroalkyl Substances

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04619

— Hao Wang, Yaqing Han, Shuo Tian, Mengke Wang, and Shun Wang 2025-10-20 14:28:11

[ASAP] A Perspective on Current and Future Metric Tools

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04727

— Francisco Pena-Pereira and Juan L. Benedé 2025-10-20 13:12:34

[ASAP] Selected-Ion Flow-Tube Mass Spectrometry (SIFT-MS) for Real-Time Quantitative Measurement of Electrochemical Carbon Dioxide Reduction Reaction Products

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04792

— Timothy M. Gibson, Madeline LeBreton, Andrew Wang, Amirhossein Rakhsha, Robert Black, and Drew Higgins 2025-10-20 16:02:48

[ASAP] Two-Dimensional FAIMS-TIMS Separation for Probing Structural Diversity of Peptides with Resolution Exceeding 6500

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05173

— Junhui Li, Xixuan Gu, Yongqi Lei, Kaiqun Wu, Zhonghan Hu, Rong Liu, Chenlu Wang, Yong Wu, Jiancheng Yu, and Keqi Tang 2025-10-20 16:39:45

[ASAP] Metal–Organic Frameworks (MOFs) for Chiral Separation and Biosensing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05729

— Hani Nasser Abdelhamid and Ali J. Chamkha 2025-10-20 10:13:32

[ASAP] Characterization of Lipid Epi-Metabolites/Reactions as Diagnostic Biomarkers for Idiopathic Pulmonary Fibrosis by Lipidepifind

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c00277

— Xinguang Liu, Yunfan Zhao, Yang Xie, Yanmin Shi, Jianya Yang, Yan Du, Jinyan Wu, Yitong Gao, Ang Zhang, and Jiansheng Li 2025-10-17 18:55:42

[ASAP] Interphase Interaction Effects on Lateral Migration of Cells in Microchannels

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03707

— Kai Zheng, Zhaomiao Liu, Siyu Zhao, Nan Zheng, Chenchen Zhang, Yan Pang, and Xiang Wang 2025-10-17 16:25:53

[ASAP] Single-Atom Nanozymes in Analytical Chemistry: Opportunities and Challenges

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05006

— Eslam M. Hamed, Mostafa M. Elsaady, and Sam F. Y. Li 2025-10-17 12:43:24

[ASAP] Achieving Low-Energy fs-LIBS with a Microwave Plasma Torch: A Feasible Method for the Development of a Portable fs-LIBS Measurement System

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04082

— Bingyu Wei, Shengping Liu, Liangyong Zhao, Zuoming Zhu, Jingfeng Xie, Youning Chen, Shengbin Shi, Shujia Wu, Qiang Zeng, Dongbin Qian, Xiaoliang Liu, Jie Shen, and Zuoye Liu 2025-10-16 18:10:54

[ASAP] Characterization of the Intact Proteomic Profile of Senescent-Associated Secretory Phenotype by Top-Down Mass Spectrometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02694

— Mozhgan Boroumand, Amit Dey, Kellye Cupp-Sutton, Tomas Pierce, Dimitrios Tsitsipatis, Allison B. Herman, Si Wu, and Nathan Basisty 2025-10-14 10:31:54

[ASAP] Discrete Entity Analysis via Microwave-Induced Nitrogen Plasma–Mass Spectrometry in Single-Event Mode

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04341

— Ana Rua-Ibarz, Flávio V. Nakadi, Eduardo Bolea-Fernandez, Antonio Bazo, Beatrice Battistella, Anna Matiushkina, Ute Resch-Genger, Carlos Abad, and Martín Resano 2025-10-14 08:53:15

[ASAP] A Microfluidic Colorimetric Biosensor Integrated with Water-Soluble Nonwoven Fabrics for Collection and Detection of Bacterial Aerosols

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04857

— Yu Cui, Meixuan Li, Jing Yuan, Fengzhen Yang, Kaiyuan Jia, Yiming Dong, Qiang Zhang, Jianhan Lin, Jianmin Zhang, Li Li, and Lei Wang 2025-10-14 17:30:58

[ASAP] Multiplex and Spatiotemporal Detection of Single-Cell Antibody Secretions Using Protein-Patterned Microwells

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03396

— Julie Van Lent, Karen Ven, Maya Imbrechts, Nick Geukens, Paul Declerck, Karen Vanhoorelbeke, and Jeroen Lammertyn 2025-10-13 14:46:06

[ASAP] Physicochemical Tuning of Bispecific Antibody Fragment Immobilization for Robust Digital SERS Biosensing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03980

— Jing Wang, Quan Zhou, Christopher B. Howard, and Matt Trau 2025-10-13 12:05:55

[ASAP] Creation of an Open-Access High-Resolution Tandem Mass Spectral Library of 1000 Food Toxicants

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03020

— Federico Padilla-González, Serena Rizzo, Caroline Dirks, Wout Bergkamp, Sjors Rasker, and Ivan Aloisi 2025-10-10 12:41:29

[ASAP] Interference Effect of Tubular Colloidal Crystal Films and Their Biosensing Applications

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03478

— Xiaoling Zheng, Bo Zhang, Liming Liu, Yizhen Wan, Tianze Wang, Yu Zhang, and Weiping Qian 2025-10-09 13:41:08

[ASAP] Microsensor Array for the Electrochemical Analysis of Hydroxyurea in Blood Samples of Children Affected by Sickle Cell Anemia

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03569

— Rajendra P. Shukla, Matan Aroosh, Remi Cazelles, Russell E. Ware, Alexander A. Vinks, and Hadar Ben-Yoav 2025-10-08 16:57:22

[ASAP] Sensor-Aided Rapid Identification of Plastic-Degrading Bacterial Strains

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04596

— Xueqing Gao, Shiling Zheng, Tianjia Jiang, and Wei Qin 2025-10-08 19:53:36

[ASAP] Simultaneous Electrochemical and SPR Detection of Dopamine Exocytosis from Single Cells and Multiple Cells Using Au Single Atom Modified Carbon Nanopipettes

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03150

— Bei Yan, Xiaochun Han, Ruihuan Zhao, Zhimin Guo, Dongxiao Li, Yu Yan, Dengchao Wang, and Xin Yao 2025-10-01 16:40:52

[ASAP] AIRPred: A Deep Learning Model Predictor for Peptide Intensity Ratios in Cross-Linking Mass Spectrometry Improves Cross-Link Spectrum Matching

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03597

— Zehong Zhang, Mei Wu, Max Ruwolt, Ying Zhu, Pin-Lian Jiang, Diogo Borges Lima, and Fan Liu 2025-08-27 14:51:47