RSS:Analytical Chemistry

Analytical Chemistry

RSS

RSS Feed

[ASAP] Azo-Enhanced Raman Rotors: Bridging Raman Scattering and Fluorescence for Hyperspectral Imaging of Live-Cell Microviscosity Dynamics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04681

— Wanyi Xie, Yajun Yu, Yaping Peng, Yuchen Tang, Zachary J. Smith, and Tingjuan Gao 2026-01-17 13:53:33

[ASAP] Electrochemiluminescence Monitoring of Microplastics Photodegradation Reveals a Superoxide Radical-Induced Hollowing-Collapse Mechanism on a COF@TiO2 Heterojunction

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06418

— Ru Wu, Guangtao Wang, Jinxiang Li, Yuqian Geng, Wenlei Zhu, Zixuan Chen, and Jun-Jie Zhu 2026-01-17 13:54:06

[ASAP] A Reusable Dual-Mode Aptasensor Based on Bipolar Electrode for Sensitive Detection of Live Clostridium perfringens

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05423

— Yuheng Yang, Wei Yuan, Wenzhuo Wang, Jiahui Chen, Daoying Wang, Weimin Xu, Zhilan Sun, and Fang Liu 2026-01-16 12:30:32

[ASAP] Natural Cell-Inspired Integration of Redox Reactant Molecules in Hierarchical MOFs Harvested for Reaction Pathway-Regulated Glycoprotein Assay

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05891

— Yi Yang, Licheng Yu, Haiyang Wang, Liang He, Pengli Bai, Xiwen He, Langxing Chen, and Yukui Zhang 2026-01-16 09:00:17

[ASAP] Ultrasensitive and Selective Detection of Chemical Warfare Agents via Electronic Modulation of Site-Specific Nucleophilicity

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06091

— Yuanxiang He, Ke Song, Xiaogang Lu, Zixuan Zhang, Runli Gao, Hongwei Ma, and Hongmei Wang 2026-01-16 19:36:08

[ASAP] AI-Assisted Multiplex SYBR Green I-Based qPCR for the Identification and Quantitative Analysis of Oral Microbiota

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06735

— Ao Long, Wenjin Chen, Shufang Zhuo, Jun Zhou, Beibei Xie, Hailun Zhou, Yiwu Qin, Kangjing Li, Chunyun Liang, Cong Liu, Lu Liu, Yigeng Liu, Xianxian Huang, Fengyuan Zhou, and Xinglu Jiang 2026-01-16 18:32:19

[ASAP] Correction to “Enabling the Identification of Dopamine Receptor Ligands from Complex Matrices Using a Cyclic Tetrapeptide”

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c08234

— Hongyu Wen, Zhisheng Lai, Jinhui Wang, Minhui Shen, Xiaoru Peng, Wei Lin, Wei Xia, Yu-Xin Ye, Jianqiao Xu, and Gangfeng Ouyang 2026-01-16 16:38:37

[ASAP] Encapsulation of mRNA in Therapeutics Like Lipid Nanoparticles Probed by Deep-UV Resonance Raman Spectroscopy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04246

— Sila Jin, Sergei V. Reverdatto, Vladimir V. Ermolenkov, Alexander Shekhtman, Young Mee Jung, and Igor K. Lednev 2026-01-15 14:25:42

[ASAP] Multiplexed Isotope-Coded Mass Spectrometry Footprinting Enables Broad Heteroatom-Residue Mapping and Uncovers Noncanonical Ligand-Binding Sites in Amyloidosis Proteins

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04456

— Kuoqi Yang, Wei Zheng, Lin Bai, Kai Wang, Jian Zhang, Yaqi Wei, Guangqiang Sun, Youhong Hu, and Ming Cheng 2026-01-15 18:39:12

[ASAP] mtDNApipe: A Pioneering Pipeline for High-Sensitivity Detection of Low-Frequency Mitochondrial DNA Mutations

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05068

— Wenjie Guo, Shengjing Li, Tianlei Sun, Zhangwen Lei, Kaixiang Zhou, Lei Zhang, Xu Guo, Feng Zhou, Yang Liu, and Jinliang Xing 2026-01-15 15:31:56

[ASAP] Alternating Current-Driven Silver Needle-Based Electrochemiluminescence Biosensor for Rapid and Low-Damage Diagnosis of Cerebral Hemorrhage with Edema

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05143

— Mi Chen, Wen Liu, Xue-Li Yang, Ke-Ming Fang, Ai-Jun Wang, Pei-Xin Yuan, Kui Liu, and Jiu-Ju Feng 2026-01-15 15:08:47

[ASAP] Quantitative Mass Spectrometry Imaging of Intact Proteins in Tissues

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05187

— Mushfeqa Iqfath, Andrew K. Swansiger, Manxi Yang, Lily Miller, Alyssa M. Moore, Emerson Hernly, Yunpeng Bai, Zhong-Yin Zhang, James S. Prell, and Julia Laskin 2026-01-15 18:54:16

[ASAP] Quantification of Organic Nitrates Using Thermal Dissociation Broadband Cavity-Enhanced Absorption Spectroscopy: Interference Suppression and Atmospheric Measurement

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05426

— Dou Shao, Min Qin, Wu Fang, Baobin Han, Jianye Xie, Xiadan Zhao, Zhitang Liao, Enbo Ren, and Zhen Wei 2026-01-15 16:56:10

[ASAP] In Situ Monitoring of Cathepsin B-Induced Mitochondrial Permeabilization by Raman Spectroscopy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05532

— Wei Li, Li Song, Shiyi Liu, Jinyu Zhu, Yuqing Wu, and Xiao Xia Han 2026-01-15 18:38:45

[ASAP] Spacer-Acceptor Synergy in Cyanide Detection: Leveraging Dual-Site Reactivity to Overcome Sensitivity-Range Trade-Offs

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05887

— Collinica Camillie Syiemlieh, Bhuvaneesh Ilango, Prabukumar Balakrishnan, Parthasarathy Venkatakrishnan, Marappan Velusamy, and Arunkumar Kathiravan 2026-01-15 09:09:39

[ASAP] Potentiostatic Current-to-Electrochemiluminescence Conversion for Real Time Detection of Low-Intensity Faradaic Events: Application to Nano-Impact Electrochemistry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05964

— Rabia Djoumer, Neso Sojic, Christophe Demaille, and Arnaud Chovin 2026-01-15 09:29:01

[ASAP] Characterization of Gas-Phase Charge-Site Isomerism in Flavonoids and Flavonoid Glycosides by Cyclic Ion Mobility-Mass Spectrometry with Computational Validation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06107

— Liping Xu, Shurui Gao, Yanqiu Wang, Lin Zhang, Hongli Li, Yu Wang, and David Da Yong Chen 2026-01-15 18:19:50

[ASAP] Plant-Derived Polysaccharide Ultrafast Purification Reinvented: A Green Aqueous Two-Phase System with Deep Eutectic Solvents for Simultaneous Decolorization and Deproteinization

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06129

— Jinxia Hu, Yu Cao, Duolong Di, Yunxia Wu, Lichun Zhao, Dong Pei, and Jianfei Liu 2026-01-15 18:53:52

[ASAP] Mass-Invariant Natural Log-Transformed Mass Spectra Enable Internal Calibration and De Novo Sequencing of Intact Proteins

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06165

— Lissa C. Anderson, Nathan K. Kaiser, Krishna Saketh Kamadana, and Xian Mallory 2026-01-15 12:31:27

[ASAP] DPM: A Deep Learning and Optimal Transport Framework for Cost-Effective Spatial Metabolomics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06903

— Bo Yao, Longfeng Yang, Chi Zhang, Yuanyuan Lv, Chenkun Yang, Li-Jun Di, Jie Luo, and Shu-Hai Lin 2026-01-15 20:11:04

[ASAP] Dual-Functional Nanoplatform for Highly Controllable ROS Generation and Monitoring in ROS-Mediated Therapy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07718

— Yifei Guo, Pei Wang, Yiwen Yan, Junli Wang, Yating He, Hong-Min Meng, Lingbo Qu, and Zhaohui Li 2026-01-15 15:18:30

[ASAP] Mineralized Remains as Adjacent Proxy for Radiocarbon Dating

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03812

— Laura Hendriks, Clémence Iacconi, Luc Robbiola, Elsa Desplanques, Negar Haghipour, Corentin Reynaud, and Loïc Bertrand 2026-01-14 15:58:44

[ASAP] ChipNMR: Hyperpolarized NMR for Noninvasive Metabolic Flux Analysis in Perfused Microfluidic Chips

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04058

— Thomas B. Wareham Mathiassen, Juan D. Sánchez-Heredia, Ke-Chuan Wang, Cajsa R. Haupt, Magnus Karlsson, Alexander Jönsson, Martin Dufva, Roland Thuenauer, and Pernille Rose Jensen 2026-01-14 13:00:16

[ASAP] Chitosan Nanomaterials: A New Revolution in Biosensors for Disease Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05061

— Xiaohua Wang, Guodong Huang, Heqi Li, Yushan Li, Khent Primo Alcantara, Chibo Liu, Chunjing Zhang, and Zheng Jin 2026-01-14 14:40:44

[ASAP] Super-Resolution Fluorescence Imaging Reveals the Role of CD24 Clusters in NSCLC Proliferation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05213

— Jincheng Wang, Baofeng Li, Meng Li, Longxiang Li, Xinyang Chen, Hongda Wang, Guangxin Zhang, Jing Gao, and Ti Tong 2026-01-14 19:53:33

[ASAP] Methods for Blood Separation and Detection in Laboratory, On-Site, and Home-Based Scenarios

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05465

— Suqi Shi, Xinjie Wang, Yijiang Zhou, Mingji Wei, Ning Yang, and Wenhao Hui 2026-01-14 13:31:37

[ASAP] Background-Free Nanopore Decoding of microRNA Expression Patterns Using Circular Diagnostic DNA

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05537

— Soma Emura, Nanami Takeuchi, Tomoko Ohshima, Kazuhito Satomura, and Ryuji Kawano 2026-01-14 14:19:44

[ASAP] A Self-Powered Wearable Mechanoluminescent–Hydrovoltaic Patch for Multimodal Sensing Application and Energy Harvesting

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05546

— Zhechen Zhang, Yuetong Tian, Shujia Wang, Zhida Gao, Yan-Yan Song, Li-Ping Mei, and Junjian Zhao 2026-01-14 14:39:56

[ASAP] Plug-and-Play Photo-Initiated CRISPR–Cas12a One-Pot Nucleic Acid Detection via Universal Repeat RNA Acylation Strategy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05769

— Jinlian Du, Xingxiang Pu, Tongyan Yuan, Fang Peng, Jingjing Hu, Han Li, Bojie Chen, Jiaming Luo, Sheng Li, Yuling Teng, Xinyue Zhu, Weiming Chen, Qingqing Xie, Ling Jiang, Erhu Xiong, and Ronghua Yang 2026-01-14 14:39:45

[ASAP] Ultrasensitive Detection of Cardiac Troponin I via CRISPR/Cas12a-Mediated Liposomal Amplification Coupled with Electrospray Ionization Mass Spectrometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05804

— Xiang Chen, Chunxiang Mao, Yuanji Gao, Chaoting Shi, Yu Wang, Zhuolin Jin, Bing Xia, and Yan Zhou 2026-01-14 19:12:03

[ASAP] Wettability-Enhanced Photothermal Vertical Flow Biosensor on a Syringe for PSA Detection Using TaTe2 Nanosheets

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05980

— Yan Huang, Luyao Feng, Manyan Wu, Xuan Gao, Yongxiang Ji, Ying Liu, Wanli Wang, Tailin Xu, and Changyan Sun 2026-01-14 15:29:48

[ASAP] Terahertz Metasurface with Ultrastrong Hotspots Empowered by QBIC

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06405

— Shuocheng She, Jiachen Zuo, Yang Li, Liu Sun, Yaowei Dai, Zekun Yang, Jinwu Zhao, Lei Wang, Wenxia Wang, Pandeng Hou, Qiuhong Qu, Yizhu Zhang, and Mingxia He 2026-01-14 20:00:00

[ASAP] Hemin-DNA Switch-Assisted Microfluidic Chemiluminescence Immunoimaging for Rapid and Quantitative Screening of Specific Hybridomas

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07461

— Wencheng Xiao, Hang Ao, Nilin Wu, Jun Sun, Wenrui Hu, Yunlong Chen, Jie Wu, and Huangxian Ju 2026-01-14 20:18:08

[ASAP] Pore Environment Engineering in Al-MOFs Enables Thermodynamic–Kinetic Synergy for High-Resolution Chromatographic Separation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07548

— Cheng-Yu Rong, Shurui Gao, Xiao-Yi Fu, Yu Wang, Ming Xu, and Zhi-Yuan Gu 2026-01-14 20:17:08

[ASAP] TROP2 Promotes Tumor Cell Migration through Downregulation of DSG2 Revealed by Super-Resolution Fluorescence Imaging

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04303

— Longxiang Li, Meng Li, Baofeng Li, Jincheng Wang, Haijiao Xu, Jinrui Zhang, Yan Shi, Yong Liu, Jilin Tang, Jing Gao, and Hongda Wang 2026-01-13 19:53:47

[ASAP] Evaluation of the Average Molecular Weight of Polyelectrolytes via Pulsed Streaming Potential Measurements

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04311

— Xinxin Guo, Lei Zhao, Zhaowei Qu, Jing Wu, Khalid Mohammed Adam, Xiayan Wang, and Qiaosheng Pu 2026-01-13 17:54:06

[ASAP] Optimized Substrates for Analysis of an Individual Atmospheric Particle Across Multiple Microspectroscopy Techniques: Fabrication and Characterization

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05491

— Katherine R. A. Kolozsvari, Emily J. Costa, Holly P. Lawson, Ryan D. Davis, and Andrew P. Ault 2026-01-13 12:32:10

[ASAP] Self-Powered Anti-Interference Photoelectrochemical Immunosensor Enabled by a Ferroelectric Hybrid Coupled with a Platinum-Doped Peptide Hydrogel

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05611

— Hao Wang, Ying Zhao, Zhiyue Cai, Gao-Chao Fan, and Xiliang Luo 2026-01-13 20:00:00

[ASAP] Single-Particle Nanoplastic Identification by Liquid–Liquid Interfacial Assembly for Correlative SERS-SEM/EDX

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05660

— Feiyue Xing, Weiman Duan, Zhangmei Hu, Peng Tang, Jian Xiong, and Meikun Fan 2026-01-13 20:35:36

[ASAP] Dual Protease-Mediated Proteolysis Coupled with Ultrafiltration for System-Level Profiling of Drug Targets and Conformational Dynamics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05671

— Xuefang Dong, Jingchen Shi, Yanyan Zhao, Liang Zhao, Xiuling Li, and Xinmiao Liang 2026-01-13 20:07:10

[ASAP] Recruitment of Enzymatic Labels via Glycan-Lectin Interactions for Electrochemical Immunosensing of Anti-dsDNA Antibodies

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05740

— Xiaoxia Chen, Min He, Wenqi Tang, Yiting Chen, Ziluan Zhu, Jingjing Xu, Qiong Hu, and Li Niu 2026-01-13 19:34:07

[ASAP] In Situ and Loss-Free Detection of Nitrate Radical via Open-Path Cavity-Enhanced Absorption Spectroscopy: Indoor Air Application

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05764

— Yiming Wang, Xiaorui Chen, Jie Wang, Zelong Zheng, Hongxia Liu, Zheng Li, Shaojia Fan, and Haichao Wang 2026-01-13 12:57:44

[ASAP] Do We Really Need Extra Signal-Enhancing Techniques for Nanoplastic Detection? The Mie-Resonance-Assisted Self-Nanolensing Effect Enables Routine Raman Analysis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05839

— Gogyun Shin, Juhui Seo, Jeonghyun Lim, Enxi Jin, and Dongha Shin 2026-01-13 18:56:09

[ASAP] Application of Engineered Split Aptamers in Fluorescence-Colorimetric Dual-Mode Detection of Chloramphenicol

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06138

— Hualin Guo, Pengfei Ma, Yu Li, Peifang Chen, and Zhouping Wang 2026-01-13 11:30:52

[ASAP] Lipid-Mimicking Fluorescent Probe for Selective Bacterial Imaging and Rapid Antibiotic Screening

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06354

— Chao Wang, Rupeng Bu, Xinming Guo, Baosheng Ge, and Fang Huang 2026-01-13 16:17:25

[ASAP] Combined Confocal Dynamic Light Scattering and Fluorescence Correlation Spectroscopy as an Advanced Technique to Characterize Colloidal Quantum Dot-Gold Nanoparticle Hybrid Systems

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06564

— Pierre Bauer, Ali Dabbous, Sébastien Pairis, Vincent Maurel, Fabien Dubois, and Aude Barbara 2026-01-13 19:30:40

[ASAP] Self-Monitoring Photoelectrochemical Sensing Platform Enabled by Dual-Channel Potential Resolution and PCA Outlier Recognition

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06682

— Yong Hao, Haiyang Li, Yujia Dong, Wenli Zhao, Nuo Zhang, and Hongmin Ma 2026-01-13 12:32:57

[ASAP] Ferrocene-Based Zr/Ni Bimetal–Organic Frameworks for Ratiometric Aptamer Sensors Enabling Efficient Dopamine Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06788

— Xiaoyan He, Zhiqiang Wang, Jing Li, Yanling Liang, Yuanyuan Lu, Xin Tian, and Xiaoquan Lu 2026-01-13 13:52:02

[ASAP] Cu2O@Conductive MOFs Heterostructure with Efficient Photocarrier Separation for Sensitive Photoelectrochemical Detection of H2S

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07007

— Zhijie Xie, Zhanglin Weng, Cuiying Lin, Bin Qiu, Chuanhui Huang, and Zhenyu Lin 2026-01-13 16:18:05

[ASAP] Ultrasound-Assisted SERS Imaging for Chemical Visualization and Matching of Etomidate-Contaminated Fingerprints

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07118

— Yating Zhang, Mengyuan Liao, Zehua Wang, Zhonghan Xu, Bowen Li, Binbin Zhang, Buyi Xu, Rongji Yang, Guoyun Zhou, Chong Wang, Jiujuan Li, Yuanming Chen, Shouxu Wang, Wei He, Yipeng Liu, and Yan Hong 2026-01-13 19:30:15

[ASAP] In Situ Polymerization of Vinyl-Functionalized Perovskite for Polarity-Switching Photoelectrochemical Enantioselective Sensing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07154

— Huan Wang, Cuicui Du, Ziqian Wen, Xiaohua Zhang, and Jinhua Chen 2026-01-13 12:50:58

[ASAP] Enhanced Electrochemiluminescence of Zn2+ Aggregation-Induced Dual Stabilizers Capped Au Nanoclusters and Its Immunosensing Applications

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07292

— Tianyuan Song, Fuwei Zhang, Rongke Zhang, Feiyan Cai, Qi Li, Li Fu, and Yingshu Guo 2026-01-13 18:19:13

[ASAP] Highly Sensitive Noninvasive Hemispherical Fiber Optic Photoacoustic Sensor Utilizing Dual Radial and Angular Resonant Modes for Simultaneous Multigas Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07830

— Guojie Wu, Linsong Zhang, Tianli Gao, Zhenfeng Gong, Yuchen Guan, Jiawei Xing, Ming Zhang, Wei Peng, and Liang Mei 2026-01-13 20:12:35

[ASAP] Rotating Magnetic Field-Enabled Metasurface-Regulated Luminescence Strategy for Extracellular Vesicle Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05071

— Zihui Liang, Peilin Wang, Zhenrun Li, Wenyan Li, and Qiang Ma 2026-01-12 16:51:37

[ASAP] Photoacoustic Detection of Atmospheric Peroxy Radicals through Ethane-Based Chemical Amplification

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05228

— Gaoxuan Wang, Ahmad Lahib, Marius Duncianu, Qian Gou, Philip S. Stevens, Sébastien Dusanter, Alexandre Tomas, Markus W. Sigrist, and Weidong Chen 2026-01-12 09:28:52

[ASAP] SABRE Acethydrazide as a Co-Substrate Agent for Quantitative Analysis of Submicromolar N-Heterocyclic Compounds Using Parahydrogen Hyperpolarization

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05273

— Quy Son Luu, Quynh Thi Nguyen, Seokki Yun, Hung Ngo Manh, Ki Hun Kim, Jiyeong Hong, Nicholas Whiting, Dinh Van Nguyen, Seyoung Yang, Uyen Thi Do, Jihyun Yoon, Dong-Ku Kang, Jihyun Kim, Sang Uck Lee, and Youngbok Lee 2026-01-12 09:40:41

[ASAP] Nonmodified Strategy Enabled Proteome-Wide Mapping of Catechol Derivatives Interactome

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05567

— Zichun Qiao, Xiaozhe Zhang, He Wang, Yichu Shan, Xiao Li, Chuhan Cao, Zhen Liang, Yukui Zhang, Bo Jiang, and Lihua Zhang 2026-01-12 15:29:07

[ASAP] Bioluminescence Recovery after Photobleaching (BRAP) Enables Real-Time Imaging of Self-Repair Dynamics and Discovery of Modulators

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05832

— Kairong Yang, Jia Gao, Haoran Li, Yaohua Li, Wukun Liu, Peng Cao, Hui Wang, Hua Su, and Wei Wang 2026-01-12 15:55:06

[ASAP] Multistage Cascade-Hierarchical Nucleic Acid Amplification for Label-Free Ultrasensitive Electrochemical Sensing of Tumor-Associated Extracellular Vesicles

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06009

— Ying Ma, Xiang-Lan He, Jia-Qi Du, Meng-Meng Pan, Ming Wang, Ming Jiang, Xu Yu, and Li Xu 2026-01-12 09:52:42

[ASAP] Novel Ultrafast Sample-to-Answer Microfluidic Platform for Highly Sensitive On-Site Quantification of Avian Influenza Virus

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06140

— Menghao Chai, Xiaofei Liu, Jingji Liu, Feng Chen, Qiongzhang Wang, Zhengying Si, Shanshan Yu, Yichao Gan, Liping Guo, Yude Yu, Yiqiang Fan, Songyin Qiu, Yajun Zhang, and Zhao Li 2026-01-12 09:51:43

[ASAP] Machine Learning-Assisted DNA Origami Shape Sorting Using Fingerprinting Nanosensors and Feature Engineering

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06210

— Shubhajit Singha, M. Mikail Demir, Vinod Morya, Ken Halvorsen, M. Abdullah Canbaz, Arun Richard Chandrasekaran, and Mehmet V. Yigit 2026-01-12 13:31:04

[ASAP] Intra-Unit Charge Transfer Synergized with Multivalent Reversible Redox Cycle for Electrochemiluminescence Aptasensing of Streptomycin

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06644

— Xue Dong, Tong Wu, Dehao Jia, Yu Du, Tingting Wu, Hongying Jia, Yiming Jiu, and Qin Wei 2026-01-12 19:00:43

[ASAP] A Data-Driven Multifunctional Microfluidic Platform for in Vitro Safety Assessment of 5-Hydroxymethylfurfural

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06862

— Jinru Tian, Mingshuang Li, Weifei Zhang, Xuanlin Feng, Shiwei Ma, Ling Wang, Wei Li, Jin-Ming Lin, Zhisheng Wu, and Nan Li 2026-01-12 09:41:56

[ASAP] Characterization of the Lipidome of Neurons in Mouse Brain Nuclei Using Imaging Mass Spectrometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c08016

— Cristina Huergo, Laura de las Heras-García, Jone Razquin, Yuri Rueda, Cristina Miguélez, and José A. Fernández 2026-01-12 18:01:15

[ASAP] Temperature-Responsive Agarose-Based Digital Microfluidics: An In-Chip Sample Preparation To Mass Spectrometry Analysis for Trace Cells and Single-Cell Proteomics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06267

— Ling Yan, Jiacheng Fang, Huimin Zhang, Yali Lin, Dan Li, Yingyan Zhou, Lin Zhu, Zhi Zhu, Pengyuan Yang, and Zongwei Cai 2026-01-11 19:36:37

[ASAP] Self-Powered Organic Photoelectrochemical Transistor Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06716

— Chunwang Chai, Yang Zhao, Hanxiao He, Yuan-Cheng Zhu, Yazhou Wang, Hui-Min Jia, and Wei-Wei Zhao 2026-01-11 17:33:25

[ASAP] Anchoring-Detection Fluorescent Probe for Investigating Microcystin-LR-Induced Plasma Membrane Damage

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06860

— Zhaomin Wang, Tianhe Fang, Syed Turab Raza, Zhe Chen, Ping Xie, and Yong Liu 2026-01-11 18:40:44

[ASAP] A Deep Multimodal Fusion Framework Integrating SERS, Clinical Data, and Metabolomics for Noninvasive MASH Diagnosis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04917

— Weilin Wu, Dechan Lu, Yan Ni, Zufang Huang, Ming-Hua Zheng, and Jing Wang 2026-01-10 13:55:49

[ASAP] Ultrasensitive Fluorescence Detection of Lung Cancer-Related miRNAs Based on DNA Tetrahedron and DNAzyme Catalytic Reaction

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06315

— Dan Xue, Jiansheng Su, Sisi Chen, Feifei Lin, Rubing Wu, Chengyi Hong, Lan Lin, and Xiangqi Chen 2026-01-10 13:54:32

[ASAP] Protein Labeling and Intramolecular Cross-Arylation via Rational Tuning of Bis-Halogenated Pyridiniums

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07032

— Yaohong Dai, Zhijun Ruan, Tuanjie Zhang, Dongyan Yang, Yanbin Fu, Kaiwen Qin, Chenchen Ge, Li Tang, Juan Feng, Jun Meng, Ziyuan Zhou, Rui Wang, and Chuan Wan 2026-01-10 13:56:49

[ASAP] Smartphone-Coupled Dual-Signal Biosensor Based on Au NP–Chitosan Hydrogel: Colorimetric Readout and Sol–Gel Transition for On-Site Cysteine Monitoring

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07222

— Longxue Yu, Yao Zhou, Xin Wang, Lingyun Xue, Shuo Wang, Yi Liu, Xuezhen Gao, and Xunyong Liu 2026-01-10 20:00:09

[ASAP] An Absolute Quantitative Approach to Study the Desorption Step in Plasma-Based Ambient MS Methods

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03205

— Odhisea Gazeli, David Moreno-González, Marcos Bouza, Charalambos Anastassiou, George E. Georghiou, Antonio Molina-Diaz, Joachim Franzke, and Juan F. García-Reyes 2026-01-09 19:08:56

[ASAP] Neural Network Guided Global Least Squares for Quantitative Biochemical Component Analysis in Raman Spectroscopy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04593

— Zelin Peng, Junjiang Liu, Linyuan Zhao, Jisheng Zhang, Fuzhou Shen, Liansheng Wang, Alan Wang, Sinno J. Pan, and Quan Liu 2026-01-09 19:38:51

[ASAP] Microwave-Assisted One-Pot Synthesis of Medium-Entropy Oxides for Dual-Mode Electrochemical and Colorimetric Analysis of Sweat Biomarkers

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04654

— Ziyu Yin, Kaylee M. Clark, Hwa-Jin Kwak, and Tyler R. Ray 2026-01-09 09:28:12

[ASAP] Conformation-Locked Near-Infrared Probes for Real-Time Visualization of G Protein-Coupled Receptor Dimers in Living Systems

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04993

— Lancheng Wang, Yujie Wang, Peng Chen, and Chi Hu 2026-01-09 13:28:45

[ASAP] Light-Scattering In Situ Imaging for Intracellular Gene Fusion Transcript Analysis at Single-Molecule Resolution

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05086

— Peiwen Huang, Yutong Chen, Fengxia Su, Xiaofei He, Bing Li, Weiliang Liu, and Zhengping Li 2026-01-09 11:09:11

[ASAP] Antimicrobial Peptide Activity in Lipid Bilayers with Smooth-Type Lipopolysaccharides

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05474

— Wakana Hashimoto, Nanami Takeuchi, Yuki Hagiri, Mana Sato, and Ryuji Kawano 2026-01-09 12:21:28

[ASAP] Chromatogram-Kendrick Mass (CKM) Plot for Comprehensive Visualization of Pyrolysis Products in Polyolefin Blends

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05519

— Ryota Watanabe, Taiki Ozawa, Sayaka Nakamura, and Hirohmi Watanabe 2026-01-09 20:16:59

[ASAP] Ultrashort-Distance Internal Light Source-Integrated ECL-PEC Dual-Mode Molecular-Sensing Device for Highly Sensitive and Accurate Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06089

— Rong-Rong Zhao, Yu-Ling Wang, Bing Wang, Xiao-Long Fu, Zhi-Zheng Li, Shu-Wei Ren, Jun-Tao Cao, and Yan-Ming Liu 2026-01-09 10:38:09

[ASAP] Single Molecular Anchor-Assisted Nanopore Profiling of DNA Abasic Site Reactivity Dynamics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06141

— Zhuoqun Su, Wanxiao Wang, Liuxin Jiao, Jingxian Hou, Jianing Chen, Ying Wang, Di Wu, Yongning Wu, and Guoliang Li 2026-01-09 10:30:23

[ASAP] Rapid Analysis of Pacific Ciguatoxins in Fish Extracts with a Lateral Flow Assay

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06159

— Ulises G. Díaz-Avello, Vasso Skouridou, Takeshi Tsumuraya, Masahiro Hirama, Naomasa Oshiro, Mònica Campàs, and Ciara K. O’Sullivan 2026-01-09 11:44:25

[ASAP] A Three-Dimensional Printed Aptasensor Array for Simultaneous Detection of Bioactive Components and Three Coexisting Mycotoxins Based on the MXene/ZnO@Ag@Au Nanoarchitecture with Synergistic Surface-Enhanced Raman Scattering Enhancement

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06660

— Yuqi Sun, Hongjun Wu, Wei Wei, Wenjuan Fu, Chao Wang, Dongbing Liang, Enze Sheng, and Dong Zhu 2026-01-09 09:08:32

[ASAP] Tuning Lipophilicity to Develop an MMP-Independent Fluorescent Probe for Visualizing Mitochondrial Peroxynitrite in Drug-Induced Liver Injury

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06669

— Sayed Zahid Nasim, Mengzhao Zhang, Suntao Shi, Ruipeng Shen, Songhe Ni, Liangying Mi, Meirong Yi, Baoxin Zhang, and Jianguo Fang 2026-01-09 10:39:15

[ASAP] Customizable NAND Logic-Gate Biosensing System Enabled by an Engineered Methylation-CRISPR/Cas12a Consensus Sequence for Ultrasensitive DNA Methyltransferase Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06772

— Jia Zhao, Zhuqi Sui, Baoqiang Chen, Rongrong Wu, Jianguo Xu, and Haiyan Dong 2026-01-09 10:48:13

[ASAP] 13C-Isotope Tracing Structural Lipidomics for Resolving Phospholipid Metabolism Dynamics in Human Breast Cancer Cells

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06789

— Zhuoning Xie, Qirui Yu, Simin Cheng, Dan Li, Zheng Ouyang, and Xiaoxiao Ma 2026-01-09 19:39:25

[ASAP] Visualizing Breathable Temperature-Sensitive Multimodal Antimicrobial Nanohydrogels for Broad-Spectrum Sterilization

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06998

— Qingyu Meng, Xiaowen Shi, Xiao-Ming Ren, Shan Huang, Xiaojun Chen, and Jun-Jie Zhu 2026-01-09 19:10:01

[ASAP] Amphiphilic Tetraphenylethylene Derivative with Hydrophobic–Hydrophilic Complementarity to Amyloid Oligomers for in Situ Imaging and Modulation of Membrane-Disruptive Neurotoxicity

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07117

— Jian Chen, Xiongwei Tang, Yichen Hu, Huixia Feng, Guanxin Zhang, Deqing Zhang, Yanyan Huang, and Rui Zhao 2026-01-09 12:41:32

[ASAP] Unraveling Enrichment Mechanism of Paper-Based Concentrator Based on Ion Concentration Polarization: Modeling and Experiment

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07234

— Shuku Niu, Runze Sun, Rihan Ao, Zirui Li, and Yixing Gou 2026-01-09 12:27:34

[ASAP] Mid-Infrared Optical Photothermal Interferometric Microscopy of Substrate-Supported Samples

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c00959

— Caitlin E. Dunlap, Alexander J. Higgins, Alexandria Alailima Martin, Margaret E. Milligan, Mike Reppert, and Garth J. Simpson 2026-01-08 16:45:47

[ASAP] Metal–Organic Framework@Gold Nanoparticles Enables Point-of-Care Diagnostics To Have Comparable Analytical Performance to Chemiluminescent Immunoassays

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04267

— Fengli Chai, Dou Wang, Fenggang Li, Saijie Wang, Yao Chen, Yongzhi Huang, Jiuxin Qu, Shuailong Zhang, Jiangjiang Zhang, and Xingyu Jiang 2026-01-08 15:10:27

[ASAP] Ultrasensitive Biosensing Platform Based on Hydroxylamine-Enhanced Copper-Mediated Fenton-Like Reaction: Application to Cu(II) and Nucleic Acid Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04403

— Tingting Ma, Yiran Liu, and Maoguo Li 2026-01-08 15:07:33

[ASAP] Orthogonal Investigation at Single-Particle and Ensemble Levels Uncovers Lipoprotein-Extracellular Vesicle Binding

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05327

— Angelo Musicò, Roberto Frigerio, Karl Normak, Sabrina Scolari, Alessandro Gori, Paolo Arosio, Annalisa Radeghieri, Lucia Paolini, Miriam Romano, Irantzu Llarena, Sergio E. Moya, Andrea Zendrini, and Paolo Bergese 2026-01-08 09:12:13

[ASAP] Profiling Glycoproteins Enriched by Multinanoparticle Protein Corona

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05881

— Emmajay Sutherland, Tim S. Veth, Kayla A. Markuson, Anna G. Duboff, and Nicholas M. Riley 2026-01-08 20:34:04

[ASAP] Near-Infrared Chemiluminescence Probe for Superoxide Anion Imaging in Alzheimer’s Disease

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06051

— Chuanyu Mao, Zhangdong Wang, Shuainan Liu, Xiaoyu Li, Yuhan Wang, Ruxiang Luo, Min Yang, Chongzhao Ran, Yueqing Gu, Peng Wang, and Jing Yang 2026-01-08 10:09:15

[ASAP] DNA Hydrogel-Templated Synthesis of Electrochemiluminescence Active Gold Nanoclusters with T7 Exonuclease Amplification for Ultrasensitive Microcystin-LR Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06262

— Aobo Feng, Zhongdi Du, Yajie Zhou, Zefeng Hua, Yudie Sun, and Kui Zhang 2026-01-08 15:06:35

[ASAP] Substituent-Driven Electronic Modulation of Azo Bond: Enabling the Design of Ultrafast and Exceptionally Sensitive Fluorescent Probe for Hypoxia

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06307

— Wenjie Zhao, Linghe Bai, Xin Zhao, Huiying Jin, Yanxia Nan, Yanjie Zhao, Zhenqi Zhang, Xinyu Wang, and Jinli Hu 2026-01-08 17:31:07

[ASAP] High-Resolution Mass Spectrometry for Nitrate Aerosol Isotopologue Quantification: Method Development, Calibration, and Application to Atmospheric Samples

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06533

— Wendell W. Walters, Addison Bowen, and Meghan E. Weatherly 2026-01-08 15:47:41

[ASAP] An Iodinated BODIPY-Based Probe for the Selective Mapping and Disassembly of Amyloid-β Aggregates In Vivo

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06741

— Mingguang Zhu, Lijun Ma, Ran Liu, Fanghui Liang, Zixuan Zhang, Guoyang Zhang, Yulong Jin, Xuefei Wang, and Zhuo Wang 2026-01-08 13:32:31

[ASAP] Gold Nanocluster-Based Sensor Array with PCA-Assisted Pattern Recognition for Discriminating Multiple Antibiotics in Different Complex Biological Samples

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06795

— Pingping Liu, Jiaheng Shi, Ying Wang, Peijian Cao, Lei Xue, Shixi Song, Shenghao Xu, Qiansi Chen, and Yonghong Wang 2026-01-08 13:54:48

[ASAP] Electrochemical Detection of Organophosphates Using Dual-Modal Enzyme-Based Biosensors

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04795

— Zachary T. Johnson, Scott A. Trammell, Joyce C. Breger, Jeffrey S. Erickson, Meghna Thakur, Igor L. Medintz, and David A. Stenger 2026-01-07 15:53:47

[ASAP] Nanoconfinement Effect and CuxO Nanorod Electrocatalysts Enhance COF@Lu Electrochemiluminescence for Biosensing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05013

— Qianqian Cai, Hongkun Li, Anyang Shi, and Guifen Jie 2026-01-07 17:16:55

[ASAP] A Superoxide Anion-Responsive NIR Fluorogenic Probe Unravels Aucubin’s Dual-Axis Therapeutic Mechanism in Hypoxic Pulmonary Hypertension via Ferroptosis Suppression and Oxidative Injury Mitigation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05233

— Xunkai Wang, Xinyu Song, Feifei Yu, Yang Yu, Jinhan Zhang, Yanlong Xing, Fabiao Yu, and Kun Dou 2026-01-07 16:20:42

[ASAP] A GC–MS Data Analysis Platform for Untargeted Metabolomics with Enhanced Coeluting Peak Resolution

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05471

— Xing-Cai Wang, Chang Yang, Hang Lv, Xue-Juan Zhang, Wan-Ting Zhou, Peng Lu, Yongjie Yu, Haiyan Fu, and Yuanbin She 2026-01-07 12:26:22

[ASAP] Strong Self-Off Biosensor Based on Proximity-Induced DNA Strand Displacement Triggered Controlled Release for Dual-Mode Sensitive Analysis of Neuron Specific Enolase

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05724

— Wenxin Qu, Lu Zhao, Xianzhen Song, and Caifeng Ding 2026-01-07 16:27:55

[ASAP] Light-Driven Upconverting Nanoparticles-Based Nanodevice for Accurate Subcellular Dual Molecular Imaging and Combinational Tumor Therapy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05888

— Ruoyan Li, Huanhuan He, Jing Feng, Luna Guo, Peng He, Weiling Song, Hong Zhou, and Xuemei Li 2026-01-07 16:30:10

[ASAP] DSPE-Ti-Chip: A Dual-Functionalized Microfluidic Device for High-Efficiency Isolation of Extracellular Vesicle from Microvolume Biofluids

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05906

— Guoshan Hou, Yan Dong, Min Zhang, Qi Yang, Baofeng Zhao, Zhen Liang, Yukui Zhang, Huiming Yuan, and Lihua Zhang 2026-01-07 14:07:35

[ASAP] Mapping C═C Positions in Branched Fatty Acid Esters of Hydroxy Fatty Acids by Oxygen Attachment Dissociation Mass Spectrometry Coupled with Chemical Labeling

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05926

— Xin-Ze Wu, Huan-Ran Yin, Feng Ji, Na An, Xiu-Feng Fu, Xiao-Dong Li, Quan-Fei Zhu, and Yu-Qi Feng 2026-01-07 19:04:24

[ASAP] Ultrasensitive Electrochemical Biosensor for DNA Methylation Detection Based on Fe-MOF/PANI and Catalytic Hairpin Assembly Cascade Reaction

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06027

— Biyao Mao, Mengyu Kang, Jinhui Li, Bin Huang, Herui Wen, and Jialin Zhang 2026-01-07 15:17:30

[ASAP] A Relay CRISPR/Cas12a System for Extraction-Free and Ultrasensitive Detection of Staphylococcus aureus in Complex Food Samples

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06345

— Kun Wang, Wanli Wang, Yufeng Hu, Xiaoyang Li, Haoyu Yu, Xin Xia, Tianhan Kai, and Mei Wen 2026-01-07 16:28:47

[ASAP] Molecularly Imprinted Polymer-Based Electrogenerated Chemiluminescence Sensor for Sensitive and Selective Fentanyl Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06407

— Arati Biswakarma and Wujian Miao 2026-01-07 13:19:42

[ASAP] Fouling-Proof Nanopore for Detecting Caspase-3 in Complex Biological Fluids

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07025

— Shujie Zhang, Ruina Zheng, Weiling Yu, Yujun Mei, Jin-Xuan Fan, Bo Liu, Yuan-Di Zhao, and Wei Chen 2026-01-07 16:23:38

[ASAP] Correction to “Nano Self-Assembly for Apoptosis Induction and Early Therapeutic Efficacy Monitoring”

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07618

— Xiaoyi Meng, Yue Cheng, Fang Wang, Zhaogang Sun, Hongqian Chu, and Yong Wang 2026-01-07 18:12:37

[ASAP] Acoustofluidic Plasmapheresis System Designed for Ultralow Blood Volume Applications

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04042

— Amal Nath, Sara Marie Larsson, Andreas Lenshof, Wei Qiu, Thierry Baasch, Linda Nilsson, Thomas Thymann, Stanislava Pankratova, Magnus Gram, David Ley, and Thomas Laurell 2026-01-06 19:04:45

[ASAP] HERO: A Memory-Efficient and Fast Structured Low-Rank Reconstruction Algorithm for Accelerated Hypercomplex NMR

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05054

— Ze Fang, Yida Chen, Yao Luo, Yu Yang, Enping Lin, and Zhong Chen 2026-01-06 20:25:13

[ASAP] Fabrication and Biosensing Application of SiO2–TiO2 Hybrid Inverse Opal Fabry-Pérot Layers

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05096

— Bo Zhang, Xiaoling Zheng, liming Liu, Yizhen Wan, Tianze Wang, Yuxin Zhai, Yu Zhang, and Weiping Qian 2026-01-06 13:14:31

[ASAP] Capacitive Lateral Flow Test for Sub-fM Analysis of Serum HER-2/neu Using a Magnetic Cellulase-Linked Aptamer Sandwich Strategy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05265

— Suchanat Boonkaew and Elena E. Ferapontova 2026-01-06 13:33:27

[ASAP] TIPP: A Novel Iodoacetamide Reaction-Induced Protein Precipitation Approach for Proteome-Wide Ligand-Target Identification

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05384

— Yanni Ma, Jiahua Zhou, Bangtong Guan, Xiaolei Zhang, Jiayi Wang, Jiayang Yan, Keyun Wang, and Mingliang Ye 2026-01-06 18:16:42

[ASAP] MOF-Powered MicroRNA Catch for Ultrasensitive Breast-Cancer Screening

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05884

— Qi Sun, Zhi-Chao Lu, Rui-Cheng Li, Zheng-Xian Zhang, Jing-Lian Su, Cheng Wang, Huai-Song Wang, Xing-Hua Xia, and Ya Ding 2026-01-06 13:13:31

[ASAP] A Triple-Channel Fluorescent Sensor Array Based on Carbon Dots for Simultaneous Discrimination and Detection of Antiseizure Medications and Psychotropic Drugs in the Treatment of Epilepsy Comorbidities

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06384

— Tongyan Bao, Xinghang Yin, Yujia Zhong, Yu Zhang, Ting Zhang, Shiyi Luo, and Rui Yang 2026-01-06 13:38:32

[ASAP] Multifiber Dimension-Conversion Laser-Induced Breakdown Spectroscopy (MFDC-LIBS): Real-Time Spatially Resolved LIBS for Enhanced Quantification in Heterogeneous Matrices

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06441

— Ze Tian, Yue Tang, Weiheng Kong, Mengjiao Zhu, Lei Lei, Qingyu Lin, and Yixiang Duan 2026-01-06 16:42:45

[ASAP] Lysosome-Targeted Dual-Functional Probe Capable of Detecting Acute Kidney Injury via In Vivo Imaging and Urinary Albumin Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06826

— Siyu Jiang, Bo Dai, and Guoqiang Feng 2026-01-06 12:34:40

[ASAP] Correction to “Time-Lapse Deep Learning for Single-Cell Subcellular Structural Phenotypic Antimicrobial Susceptibility Testing”

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07908

— Wenwen Jing, Tianran Zhang, Xi Chen, Xiaofei Wang, Ying Fan, Meng Feng, Kai Jin, Guodong Sui, Chenbin Liu, and Xunjia Cheng 2026-01-06 16:18:27

[ASAP] A Chemically Inducible Multimerization System for Tunable and Background-Free RTK Activation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05190

— Yuanmin Zheng, Jinyu Fei, Abhirup Chakrabarti, and Ruobo Zhou 2026-01-05 12:30:53

[ASAP] Simultaneous High-Precision 13C Isotope Ratio Analysis of CO2 and CH4 Using an FDM-OA-CEAS Sensor

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05460

— Yubing Yang, Xinhan Sheng, Guangzhen Gao, Hui Yang, and Tingdong Cai 2026-01-05 09:21:29

[ASAP] Multiplatform Benchtop NMR Interlaboratory Study of Model Liquid Dosage Forms of Pharmaceutical Products

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05487

— Katharine T. Briggs, Frank Delaglio, Marc B. Taraban, Robert G. Brinson, Luke Arbogast, Brendan Lichtenthal, Matteo Pennestri, Robert Espina, Hector Robert, Juan F. Araneda, Paul Hui, Susanne D. Riegel, Kevin Nott, Leonid Grunin, Innokenty Nikolaev, Thomas Reininger, Y. Bruce Yu, and John P. Marino 2026-01-05 13:53:58

[ASAP] Solid-State Nanopore-Based Cell Analysis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05607

— Kewen Song, Ruidong Gao, Xinyi Pan, Shuhan Yang, Yu Dai, Xiaojin Zhang, and Fan Xia 2026-01-05 13:21:51

[ASAP] A High-Density Microchamber Array for the Analysis of Extracellular Vesicles Derived from Single Cells under Drug Treatment

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05621

— Lucien R. Stöcklin, Claudius L. Dietsche, and Petra S. Dittrich 2026-01-05 16:21:21

[ASAP] UV-Mediated Enzyme-Like Activity Reversal Strategy To Regulate Nanozymes for Detection and Elimination of Bacteria

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05879

— Maoying Peng, Feng Shi, Haibing Zhu, Juan Li, Run Zhu, Chuanli Ren, and Zhanjun Yang 2026-01-05 14:52:06

[ASAP] Cation-Induced Assembly Confers Aqueous Stability on Magic-Sized Clusters for Enhanced Electrochemiluminescence

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06196

— Junjun Ge, Haoyang Zhang, Xufeng Chen, Haoyuan Song, Tao Zhou, Jie Guan, Yue Cao, Chang-Jie Mao, Jun-Jie Zhu, Yang Zhou, and Yuanyuan Wang 2026-01-05 09:59:15

[ASAP] Hyaluronic Acid-Gentamicin Hydrogel and pH Indicator Mediated by Mesoporous Silica Nanoparticles as Antibacterial and Indicatable Wound Dressings for Real-Time Monitoring of the Healing Process

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06240

— Wenqian Bai, Zheng-Zhi Yin, Huwei Bian, Laidi Xu, Tao Jiang, and Yong Kong 2026-01-05 18:07:29

[ASAP] In Vivo Ratiometric Electrochemical Detection of Hypochlorous Acid in Living Brains Using a Methylene Blue-Benzoyl-Based Microsensor

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06562

— Xingchen Tan, Wenhui Wang, Cong Luo, Qian Wang, Huihui Wang, Hui Pan, Haoyue Xiang, and Hui Gu 2026-01-05 16:43:22

[ASAP] Analysis of Proteins and Peptides by Electrokinetic Stacking Coupled with Paper Spray Mass Spectrometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06786

— Lahiru Wedasingha, Magnus Rydberg, Merlin L. Bruening, and Nicholas E. Manicke 2026-01-05 09:30:50

[ASAP] Lateral Flow Strip-Compatible Nucleic Acid Testing for Facile Diagnosis of Infectious Pet Diseases

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06890

— Ting Zheng, Yanying Wang, Xianming Li, and Peng Wu 2026-01-05 10:56:43

[ASAP] Design of a NIR-I Viscosity-Sensitive Fluorescent Probe for Tracking Nuclear Physiological Changes During Different Cell Cycle Stages

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05382

— Jiaying Yu, Hao Zhang, Shen Yuan, Congyong Sun, Li Zhang, Chao Luo, and Qilong Wang 2026-01-04 17:31:01

[ASAP] Computer-Customized Design of Graphene Oxide Logic Circuit Catalytic Hairpin Assembly Linkage (CHA-Linkage) Enables Molecular-Level Identification of Cancer Cells

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05451

— Yuchen Song, Meiyin Liu, Zixuan Lou, Rong Huang, Dongmei Deng, Liqiang Luo, and Xiaoli Zhu 2026-01-04 18:40:15

[ASAP] Mn,Ce-CDs-Loaded MIL-53(Fe) Nanozymes Multisubstrate Sensor Array Integrated with Multiple Machine Learning Complementary Strategy for Highly Reliable Antioxidant Discrimination and Determination

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05867

— Mingming Wei, Qikun Zhang, Hongjin Huang, and Yang Shu 2026-01-04 17:31:41

[ASAP] Tracking the Electrochemical–Mechanical Evolution by Coupled Operando X-ray Diffraction and Strain Monitoring

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06272

— Weifeng Huang, Hongjing Dai, Xinrong Chen, Li Zhang, Yi Qian, Biao Li, and Xiang Li 2026-01-04 15:52:26

[ASAP] Fe–N3S Single-Atom Nanozyme with Asymmetric Coordination for Ultra-Low-Background Colorimetric Immunoassays

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c07715

— Zhichao Yu, Mingdi Xu, Man Xu, Jiayu Gu, Hong Xue, and Dianping Tang 2026-01-04 19:52:05

[ASAP] GlypPRM: An Automated Analyzer and Quantification Tool for Glycopeptides Parallel Reaction Monitoring

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06005

— Oluwatosin Daramola, Sherifdeen Onigbinde, Moyinoluwa Adeniyi, Cristian D. Gutierrez-Reyes, Mojibola Fowowe, Vishal Sandilya, and Yehia Mechref 2026-01-03 18:50:27

[ASAP] Rapid Colorimetric Detection of Inorganic Phosphate in Eutrophic Waters via Proton-Coupled Electron Transfer in Quinhydrone

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06072

— Jehad Abdelnabi, Mohamed H. Hassan, Allison Zeiss, Jane Oppenlander, Jingyun Ye, and Silvana Andreescu 2026-01-03 13:57:44

[ASAP] Extreme Ultraviolet Photodissociation Decodes the Chain Modifications of Lipids

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06299

— Yaolu Ma, Zheyi Liu, Zhixiong Jin, Heng Zhao, Jiami Zhou, Jieying Xue, Meng Zhang, Shirui Yang, Yuanjiang Pan, Weiqing Zhang, Chunlei Xiao, Xueming Yang, and Fangjun Wang 2025-12-29 20:00:00

[ASAP] Chiral Derivatization Enables High-Resolution Ion Mobility Spectrometry of 30 Amino Acid Enantiomers

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06382

— Chi Yan, Xingyu Chen, Wenqing Gao, Chunlan Tang, Liwen Du, Chengyi Xie, Feng Xu, Keqi Tang, and Jiancheng Yu 2025-12-26 20:00:00

[ASAP] A Laser-Engraved Wearable Patch Aptasensor Based on Tetrahedral DNA Nanostructures for In Situ Detection of Cortisol in Sweat

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05221

— Ruina Zheng, Shujie Zhang, Weiling Yu, Yujun Mei, Qiancheng Zhan, Zhanyin Lin, Bowen Xue, Jinxuan Fan, Bo Liu, Yuan-Di Zhao, and Wei Chen 2025-12-22 20:00:00

[ASAP] Simultaneous Detection of SARS-CoV-2 Nucleocapsid Protein and RNA by Aptamer-Based Proximity Ligation and Quantitative PCR

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05529

— Emil A. Zaripov, Carlos Gu, Kalem Holmes, Yuchu Dou, Aliaksandra Radchanka, Drake Johnson-Scherger, Petr Kasyanchyk, Abdullah Khraibah, Nandanee Mulloo, and Maxim V. Berezovski 2025-12-22 20:00:00

[ASAP] Noninvasive Dynamic Cell Viability Monitoring Based on Diffraction Height Fingerprint Spectra

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05214

— Zhaoyuan Zhang, Tongge Li, Haodong Liu, Ni Yu, Ranran Han, Xiao Du, Ning Liu, Jiahao Ding, Si Chen, and Ning Yang 2025-12-19 20:00:00

[ASAP] Upconversion Nanoparticle Tagging of Explosives and Post-blast Residue Analysis by Single Particle ICP-MS

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04884

— Tim Steinwachs, Sophia Jolanta Baumann, Tilo Daniel Schachel, Thomas Hirsch, and Uwe Karst 2025-12-18 20:00:00

[ASAP] MED: Multiplexed, Entropy-Driven Catalysis, Single-Nucleotide-Resolved ctDNA Detection

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06199

— Lijia Yuan, Ting Xiao, Jing Li, Weifeng Duan, Duojie Bianba, Ligai Zhang, Yuan He, Dunquan Xu, Muzhen Da, Jing Sheng, Ming Chen, and Sha Yang 2025-12-18 20:00:00

[ASAP] Seawater Salinity Measurement Using Laser-Induced Plasma: Acoustic–Spectral Characteristics and Analytical Performances

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05320

— Ye Tian, Qingxi Liu, Beibei Wang, Pingsai Chu, Yuanyuan Xue, Zuohe Shi, Jinjia Guo, Yuan Lu, Wenhua Song, and Ronger Zheng 2025-12-11 20:00:00

[ASAP] Machine Learning-Guided Optimization of SABRE Hyperpolarization for α-Ketoglutarate in Acetone–Water

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05859

— Erica Curran, Sina Sadeghi, Stephen J. McBride, Karl Mattsson, Megan Pike, Rielly J. Harrison, Mustapha B. Abdulmojeed, Franziska Theiss, Patrick TomHon, Eduard Y. Chekmenev, Milad Abolhasani, and Thomas Theis 2025-12-09 20:00:00

[ASAP] Digital-to-Droplet Microfluidic Platform Powered Digital Isothermal Nucleic Acid Amplification for On-Demand Detection of Post-Transplantation Infection-Causing Viruses

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05853

— Hongting Wen, Enqi Huang, Yuzhang Chen, Ziyi Zhang, Ting Zhang, Na Yang, Zhenhua Chen, Yu Wang, Dongyang Cai, Xianming Liu, and Dayu Liu 2025-12-05 20:00:00

[ASAP] Robotic Plasma System for Rapid Activation of Mass-Produced Electrochemical Sensors

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04556

— Marina Di-Oliveira, Mariana C. Marra, Raquel G. Rocha, Teodoro R. Terra, Rodrigo A. A. Muñoz, and Eduardo M. Richter 2025-12-01 20:00:00

[ASAP] Ergosterol-Targeted Nanocatcher with High Affinity and Capture Efficiency for Ultrafast SERS Detection of Aspergillus

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05588

— Yu Xu, Shan Hu, Yunjian Wu, Junyi Chen, Fu Ze, Tianyi Ma, Kaixuan Yuan, Lina Zheng, Feng Gu, and Ying Yang 2025-12-01 20:00:00