RSS:Analytical Chemistry

Analytical Chemistry

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[ASAP] Boron–Nitrogen Co-Doped Polymer Dots as a Metal-Free and Substrate-Free Fluorescent Nanozyme for Dual-Modal Monitoring of Catechol

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04878

— Jiexi Liang, Zhimin Mo, and Li Zhou 2025-12-18 09:31:33

[ASAP] Specificity of Arsenic Stress Detection by Raman Spectroscopy During Co-Occurrences of Nitrogen Deficiency and Narrow Brown Leaf Spot

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05673

— Isaac D. Juárez, Myles Russwurm, Sabin Khanal, Sudip Biswas, Endang M. Septiningsih, Xin-Gen Shane Zhou, and Dmitry Kurouski 2025-12-18 12:12:02

[ASAP] Rational Construction of a Lipid Droplet-Targeted Redox-Responsive Ratiometric Probe for Screening of Antioxidant Drugs and Its Application in Parkinson’s Disease

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05923

— Min Deng, Zibo Zhai, Hailin Zhang, Xuelin Shi, Yaman Wen, Dan Cheng, Longwei He, and Songjiao Li 2025-12-18 12:18:41

[ASAP] Development of a Self-Activating Dandelion-Shaped DNA Nanodevice for Amplified Imaging of mRNA and Precise Gene Silencing

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06247

— Yun Han, Weijie Tong, Fei Ma, and Chun-Yang Zhang 2025-12-18 09:02:37

[ASAP] Quantitative Measurement of TFA and Other Short Chain PFAS in Environmental Samples Using 19F SSFP-CRAFT NMR

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06450

— Jeremy R. Gauthier, Andre J. Simpson, and Scott A. Mabury 2025-12-18 20:00:00

[ASAP] Scaling Peptide-Barcode Approach for Parallel Evaluation of Protein Expression from Multiple mRNA Variants

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02991

— Shun Kumano, Kazuki Tanaka, Shoko Kawakami, Mariko Yamamoto, Rena Akahori, and Akihiro Nojima 2025-12-17 09:11:07

[ASAP] Deep Learning Algorithms Enabled Visual Detection of Anthrax Biomarkers by Mn3O4 Nanozyme-Based Colorimetric Sensor Array

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03628

— Ziqian Gao, Mengxuan Liu, Lei Meng, and Na Xu 2025-12-17 11:22:50

[ASAP] VirMolAnalyte: An AI-Driven In Silico Metabolite Annotation Tool

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03906

— Guilin Hu, Jameel Hizam Alafifi, and Minghua Qiu 2025-12-17 18:07:04

[ASAP] Enhanced Sensitivity and Resolution in Biomolecular CEST NMR Experiments Using the Extended Hadamard Encoding Scheme

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04282

— Jihyun Kim, Micael Silva, E̅riks Kupče, Sundaresan Jayanthi, Adonis Lupulescu, Rina Rosenzweig, and Lucio Frydman 2025-12-17 13:31:33

[ASAP] Establishing 19F NMR for Understanding Sorbent Interactions with Per- and Polyfluoroalkyl Substances (PFAS): Ranking Affinity and Dissecting Interactions of Nanoscale Carbon Dots and β-Cyclodextrin with PFAS

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04690

— Riley E. Lewis, Cheng-Hsin Huang, Ana Katrina Tiu, and Christy L. Haynes 2025-12-17 13:22:40

[ASAP] Pure Shift 2D and 1D NMR in Tabular Domain via Complete Reduction to Amplitude Frequency Table [CRAFTps]

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04849

— Krish Krishnamurthy and Dan Iverson 2025-12-17 13:00:03

[ASAP] High-Wavenumber Raman Spectroscopy for the Identification and Biochemical Characterization of Microbial Species

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05031

— Alec B. Walter, Ezekiel Haugen, Anna S. Rourke-Funderburg, and Andrea K. Locke 2025-12-17 20:00:00

[ASAP] In-Source Fragmentation Annotation in Sterol Mass Spectrometry Imaging

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05199

— Iulia Sidorov, Nina Ogrinc, Lena Spieth, Michal Kopcil, Marieke Heijink, Hans Dalebout, Gesine Saher, Stefan A. Berghoff, Gary Siuzdak, and Martin Giera 2025-12-17 18:38:14

[ASAP] Online Electroextraction–NanoESI–MS for Rapid Analysis of Catecholamines in Urine

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05250

— Meng Zhang, Yanxiao Jiang, Qiong Wu, Hong Zhang, Kai Yu, Guangfeng Kan, Daqian Song, and Jie Jiang 2025-12-17 15:47:47

[ASAP] Mineral Phase-Resolved Quantification in LA-ICP-MS Imaging

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05398

— Barbara Umfahrer, Jakub Buday, Pavel Pořízka, Jozef Kaiser, Paolo S. Garofalo, and Detlef Günther 2025-12-17 20:39:19

[ASAP] Rapid and Sensitive Quantification of Nano- and Microplastics in Water, Sediment, and Biological Tissue by Pyrolysis-Gas Chromatography Tandem Mass Spectrometry with Dynamic Reaction Monitoring

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05604

— M. Bryan Gahn, Marcus Wharton, Asif Mortuza, David Hala, Christopher D. Marshall, and Karl Kaiser 2025-12-17 13:32:38

[ASAP] Imaging of Protein Assemblies up to 231 kDa in Tissues with Nano-DESI Mass Spectrometry

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05767

— Oliver J. Hale and Helen J. Cooper 2025-12-17 18:08:04

[ASAP] AND-Gate Logic-Controlled Catalytic Hybridization Network for Robust Dual-Mode Fluorescence-Colorimetric Detection of Breast Cancer miRNAs

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05909

— Yao Yao, Shuyan Chen, Yujun Cheng, Chuan Long, Wei Liu, Zhipeng Zhang, Qi Liu, and Xiaoqing Chen 2025-12-17 09:10:19

[ASAP] Epoxidation-Enhanced Charge-Switch Derivatization for Rapid Profiling of Monounsaturated Fatty Acid Isomers

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06149

— Sarah E. Hancock, Linda Garthwaite, Laura L. Y. Choong, Iliya Dragutinovic, Jonathan C. Morris, and Nigel Turner 2025-12-17 12:47:40

[ASAP] Deep Learning-Assisted G4 Nanowire-Enhanced Carbon Dot Biosensor for Exosomal LncRNA Artificial Intelligence Diagnosis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06416

— Ruiying Yang, Zhiyi Yan, Jiangying Ji, Jiarui Wei, Mengjiao Mei, Shang Chen, Lingbo Qu, Yongjun Wu, and Lihua Ding 2025-12-17 16:33:04

[ASAP] Stimuli-Responsive Fusion of Binary-Star Intelligent DNA System for the Signal-On Amplification Detection of Cancer-Related miRNA

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06801

— Liujing Pan, Yao Wu, Wenhao Pan, and Zai-Sheng Wu 2025-12-17 15:49:01

[ASAP] Fluorinated Side-Chain-Modified Peptides Inspired by Shark Skin for Antifouling Electrochemical Biosensing: Ultrasensitive Detection of CA15–3 in Human Saliva

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06964

— Kunpeng Yu, Xin Sun, Zhen Song, and Xiliang Luo 2025-12-17 15:13:52

[ASAP] A Simple Online Internal Standard Calibration Strategy for Single-Particle Inductively Coupled Plasma Mass Spectrometry Based on Multielement Analysis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06975

— Xiangwei Tian, Ying Wang, Peijie Yang, Dingyi Wang, Yanwei Liu, Yingying Guo, Yuning Hu, Xiaoyan Zhang, Ligang Hu, Yongguang Yin, Yong Cai, and Guibin Jiang 2025-12-17 17:34:52

[ASAP] Machine Learning-Driven Extracellular Vesicles Peptidomics Powers Precision Classification of Endometrial Cancer

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02234

— Yunhan Yang, Dandan Li, Pengfei Wu, Haonan Yang, Jia Yi, Dan Zhao, Jiawei Yu, Ji Ji, Xiaojun Chen, and Liang Qiao 2025-12-16 16:55:00

[ASAP] Probing Surface Changes in Fe–Ni Oxide Nanocatalysts with a ToF-SIMS-Coupled Electrochemistry Setup and Principal Component Analysis

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03894

— Heydar Habibimarkani, Jörg Radnik, Vasile-Dan Hodoroaba, and Elisabeth John 2025-12-16 16:54:33

[ASAP] A Workflow-Driven Multisensor Scanning System for In Situ Extensive Hyperspectral Chemical Imaging of Paintings

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04231

— Lucilla Pronti, Martina Romani, Antonella Balerna, Damiano Cappella, Stefano Tamascelli, Silvia Brandalesi, Alice Mantoan, Marco Angelucci, and Mariangela Cestelli Guidi 2025-12-16 17:24:48

[ASAP] Dual Comb Spectrometer for the Determination of Stable Isotopic Ratios of Atmospheric CO2 with Sub-Permille Precision at Atmospheric Pressure

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04845

— Jens Goldschmidt, Nicolas Brugger, Leonard Nitzsche, Ponkanok Nitzsche, Cem Dinc, Christian Weber, Ingo Breunig, Katrin Schmitt, Frank Kühnemann, and Jürgen Wöllenstein 2025-12-16 16:03:36

[ASAP] Spatiotemporal Analysis of Enzyme Activity in Lung Cancer Tissue via Deuterated Probe-Based Mass Spectrometry–Fluorescence Dual-Modal Imaging

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04865

— Yanmei Yang, Yuling Zhong, Zhao Wang, Shuai Yang, Liyuan Du, Yue Tang, Zhenzhen Chen, and Bo Tang 2025-12-16 16:27:07

[ASAP] Enhanced Integrative Diagnosis and Therapeutic Strategy for Hepatic Ischemia-Reperfusion Injury through HOCl-Sensitive Cysteine Delivery System for Targeted Antioxidant Modulation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05365

— Wen Zhang, Yanjiao Li, Dongni Yin, Xin Wang, Hui Wang, Wei Zhang, Ping Li, and Bo Tang 2025-12-16 13:23:21

[ASAP] Bottom–Up Protein Analysis Workflow for Simultaneous Characterization of Payloads, Disulfide Bonds, and Free Thiols in Antibody–Drug Conjugates

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05683

— Keting Zhou and Yu Xia 2025-12-16 11:43:18

[ASAP] NMR Spectral Alignment Utilizing a CryoEM Motion Correction Algorithm

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c02504

— Colin A. Hemme, Owen A. Warmuth, Songlin Wang, Christopher G. Williams, Alexander Thome, Leonard J. Mueller, Chad M. Rienstra, and Timothy Grant 2025-12-15 16:34:52

[ASAP] Raman Spectroscopy for In Vivo Tumor Imaging

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03986

— Ying Bao, Liming Guo, Ziwen Gao, Yuting Yan, Yujie Duan, Yao Zhao, Hao Wang, and Chunsheng Xiao 2025-12-15 15:59:19

[ASAP] AnnoTCM: An Annotation Tool for Multimodal Metabolite–Phenotype Integration in Decoding Bioactive Compounds of Traditional Chinese Medicine

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04126

— Xingyi Liang, Yixin Cui, Yanwei Tan, Yang Zhou, Xingzu Cao, Zhe Wu, Chunling Feng, Xiaodong Wen, Xudong Xing, and Hua Yang 2025-12-15 18:23:13

[ASAP] Development of a Sensitive Lateral Flow Immunoassay Using Recombinant Rabbit Single-Chain Variable Fragments Fused to a Nitrocellulose-Binding Protein

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04510

— Ngoc Minh Nguyen, Ryosuke Mukai, Makoto Nita, Fuki Yokoyama, Ngoc-Lan Thi Nguyen, Jun-Ichi Horiuchi, and Yoichi Kumada 2025-12-15 17:54:08

[ASAP] In Situ, Time-Resolved Measurements of Lithium-Ion Battery Gases During Cell Formation Using Mid-IR Laser Absorption Spectroscopy

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04714

— Raghav G. Poddar, Joshua Stiborek, Nathan J. Kempema, David Bilby, and Christopher S. Goldenstein 2025-12-15 18:37:39

[ASAP] Portable Sensor for Detecting Trifluoroacetic Acid in Bottled Water: A Visualization Method Based on Multiple Synergistically Induced Aggregation

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04785

— Haocheng Yang, Siyu Huang, Jinhong Luo, Yuting Zhou, Shengshen Gu, and Haifeng Zhou 2025-12-15 16:57:11

[ASAP] Quantum Dots-Enhanced Laser-Induced Breakdown Spectroscopy for Ultrasensitive Quantification of Trace Metals in Oils

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04793

— Wanying Ding, Shilong Xu, Youlong Chen, Congyuan Pan, Jiajie Fang, Shengjie Ma, Xin Wang, Yuhao Xia, and Yihua Hu 2025-12-15 19:09:36

[ASAP] Quantitative Detection of Serum Protein-Specific Glycosylation in Ovarian Cancer Based on a Signal-Convertible Mass-Tagged Probe Set

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05511

— Bo Sun, Yiming Zhao, Yang Li, Danzhuo Liu, Hankun Hu, Hong Cheng, and Liang Liu 2025-12-15 13:24:37

[ASAP] Ionophore-Based SERS Nanosensors for Selective Electrolyte Detection and Intracellular Mapping

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05634

— Laiqi Zhang, Zhiyu Tang, Alejandra Coronel-Zegarra, Vivian Merk, Xingquan Zhu, and Renjie Wang 2025-12-15 20:09:27

[ASAP] Chemigenetic Nanoprobe for Proximity Sensing Dynamics of Lactate Efflux

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05718

— Qin Xu, Xu Zhao, Li-Jian Chen, An-Dong Shao, and Xiu-Ping Yan 2025-12-15 17:29:09

[ASAP] Bimetallic Valence Modulation Strategy Boosted Peroxidase-/Laccase-like Activity of a MoCu-2MI MOF Nanozyme for Portable-Device-Enabled Trimodal Sensing of D-Penicillamine and Colorimetric Analysis of Phenolic Pollutants

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05901

— Daoqing Fan, Shuai Qin, Chuanping Li, Yujia Ren, Lilin Hao, Hengqian Zhang, Jiawen Han, Jingyu Hou, Juan Wang, and Shaojun Dong 2025-12-15 15:26:13

[ASAP] Superhydrophobic MXene Spherical Cavity Arrays as Surface-Enhanced Raman Scattering Sensors for Label-Free Gas Detection and Photothermal Desorption

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06271

— Guangming Zhang, Yang Wu, Wanning Dou, Mingrui Shao, Chang Ji, Zhiyang Pei, Zhen Li, Jing Yu, Chao Zhang, and Xiaofei Zhao 2025-12-15 10:01:26

[ASAP] A Versatile CRISPR/Cas12a Autocatalytic Cascade System via Structure-Switching V-Type Split Probe for Highly Sensitive DNA Diagnostics

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06488

— Zhun Lin, Zhe Pu, Jiacheng Wu, Jialin Zeng, Quanhao Dou, Miao Mao, and Yuanqing Zhang 2025-12-15 11:03:19

[ASAP] Utilizing Engineered Monobodies for the Electrochemical Quantification of Lysozyme

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c03304

— Sunanda Dey, Andrew Naser, Daniel R. Woldring, and David P. Hickey 2025-12-14 18:49:40

[ASAP] Multifunctional Composite Coating-Enhanced Flexible Microelectrodes for Chronic, High-Fidelity Neural Signal Recording

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04799

— Ji Pang, Yuyang Sun, Tingting Cheng, Jine Wang, Xuan He, Ying Xiang, Weihao Zhu, Yijia Cao, Meng Wu, Weihua Pei, Renjun Pei, and Yi Cao 2025-12-14 18:50:37

[ASAP] In-Line NMR Diagnostics of Hydroformylation Provided by the Segmented-Flow Microfluidic Regime

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05154

— Mahmoud E. A. Eid, Maria V. Nenasheva, Aleksei N. Bulgakov, Alexander V. Soldatov, Dudari B. Burueva, Elizaveta S. Kononenko, Ivan V. Skovpin, Igor V. Koptyug, Dmitry N. Gorbunov, and Alexander A. Guda 2025-12-14 13:51:11

[ASAP] Electroanalysis Using Isostatic Graphite Electrodes

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c04846

— Tasneem Omda Edrees Isaa, Ala’a Mhmoued Abdllh Alboull, Hao Jiang, Ghulam Mustafa, Tsegu Lijalem, Valentin Mirceski, and Guobao Xu 2025-12-13 14:57:33

[ASAP] Visualizing Viscosity Changes in Tumor and Rheumatoid Arthritis with a Dual-Targeted NIR Fluorescent Probe

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c05774

— Peng Lei, Pengjia Wei, Chuan Dong, Shaomin Shuang, and Minglu Li 2025-12-13 13:55:47

[ASAP] A Novel Ficoll400-Based Signal Amplification Platform for High-Sensitive Cardiac Troponin I Immunoassay

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06026

— Chaolin Guo, Meng Liu, Shuaipeng Li, Ludan Xie, Kuiqi Jin, Yang Sun, Jianqi Nie, and Zhonghu Bai 2025-12-13 16:50:57

[ASAP] Source Fingerprinting of PFOA via Full- and Intramolecular Stable Isotope Ratios of Carbon Using Orbitrap-IRMS

Analytical Chemistry

DOI: 10.1021/acs.analchem.5c06168

— Holden M. Nelson, Zhiliang Xu, Hui Li, and James J. Moran 2025-12-13 13:56:16