Resolving power (in mass spectrometry)

IUPAC RECOMMENDATIONS 2013
Resolving power (in mass spectrometry) {{{acronym}}}
mass resolving power Measure of the ability of a mass spectrometer to provide a specified value of mass resolution. Note: The procedure by which Δ(m/z) was defined and measured, and the m/z value at which the measurement was made, should be reported.
Related Term(s):
Reference(s): Revised from IUPAC. Analytical Division. Compendium of Analytical Nomenclature (the Orange Book). Definitive Rules, 1979. Compiled by J. Inczdy, T. Lengyel, A. M. Ure. Blackwell Scientific Publications, Oxford (1997). On-line corrected version: http://www.iupac.org /publications/analytical compendium (2000). IUPAC. Compendium of Chemical Terminology, 2nd ed. (the Gold Book). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997). XML on-line corrected version: http://goldbook.iupac.org (2006-) created by M. Nic, J. Jirat, B. Kosata; updates compiled by A. Jenkins.
From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.
Index of Recommended Terms

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Orange Book

ORANGE BOOK DEFINITION IUPAC. Analytical Division. Compendium of Analytical Nomenclature (the Orange Book). Definitive Rules, 1979 (see also Orange Book 2023)
Resolving power (in mass spectrometry)
The ability to distinguish between ions differing in the quotient mass/charge by a small increment. It may be characterized by giving the peak width, measured in mass units, expressed as a function of mass, for at least two points on the peak, specifically for 50% and for 5% of the maximum peak height.
IUPAC 1997 Orange Book Chapter 12
Index of Orange Book Terms

Gold Book

GOLD BOOK DEFINITION IUPAC. Compendium of Chemical Terminology, 2nd ed. (the Gold Book). Compiled by A. D. McNaught and A.Wilkinson. Blackwell Scientific Publications, Oxford (1997).
Resolving power (in mass spectrometry)
Resolving power (mass spectrometry) http://goldbook.iupac.org/R05321.html The ability to distinguish between ions differing in the quotient mass/charge by a small increment. It may be characterized by giving the peak width, measured in mass units, expressed as a function of mass, for at least two points on the peak, specifically at fifty percent and at five percent of the maximum peak height. mass resolving power http://goldbook.iupac.org/M03730.html Commonly and also acceptably defined in terms of the overlap (or 'valley') between two peaks. Thus for two peaks of equal height, masses and , when there is overlap between the two peaks to a stated percentage of either peak height (10% is recommended), then the resolving power is defined as . The percentage overlap (or 'valley') concerned must always be stated. Source: PAC, 1978, 50, 65 (Recommendations for symbolism and nomenclature for mass spectroscopy) on page 72
IUPAC Gold Book
Index of Gold Book Terms

Controversy

QUOTED TEXT FROM IUPAC RECOMMENDATIONS 2013
The IUPAC definition of resolution in mass spectrometry expresses this value as m/Δm, where m is the mass of the ion of interest and Δm is the peak width (peak width definition) or the spacing between two equal intensity peaks with a valley between them no more than 10 % of their height (10 % valley definition) [1]. Resolving power in mass spectrometry is defined as the ability of an instrument or measurement procedure to distinguish between two peaks at m/z values differing by a small amount and expressed as the peak width in mass units [2]. Mass resolving power is defined separately as m/?m in a manner similar to that given above for mass resolution [3]. These definitions of mass resolving power and resolving power in mass spectrometry are contradictory, the former is expressed as a dimensionless ratio and the latter as a mass. The definitions for resolution in mass spectrometry and resolving power in mass spectrometry come from Todds 1991 recommendations [4], and the definition for mass resolving power comes from Beynons 1978 recommendations [J. Beynon. Pure Appl. Chem. 50, 65 (1978)]. Beynons work contains no definition for mass resolution. Alternative definitions for resolution and resolving power in mass spectrometry have been proposed [5][6]. It has been suggested that resolution be given by Δm and resolving power by m/Δm; however, these definitions are not widely used. The majority of the mass spectrometry community uses resolution as defined by IUPAC. The term resolving power is not widely used as a synonym for resolution. In this document, the IUPAC definition of resolution in mass spectrometry remains in place. The definition of resolving power has been adapted from the current IUPAC definition of mass resolving power.
From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

Books defining resolution and/or resolving power

Books using resolution is m/Δm

Mass Spectrometry and its Applications to Organic Chemistry

J. H. Beynon

Elsevier, 1960

Mass Spectrometry Organic Chemical Applications

Klaus Biemann

McGraw-Hill, 1962

Lasers and Mass Spectrometry

By David M. Lubman

Oxford University Press US, 1990

ISBN 0195059298

Interpretation of Mass Spectra

Fred W. McLafferty, Turecek

University Science Books, 1993

Language: English

ISBN-10: 0935702253

Mass Spectrometry: Clinical and Biomedical Applications

By Dominic M. Desiderio

Springer, 1993

ISBN 0306442612

Practical Organic Mass Spectrometry: A Guide for Chemical and Biochemical Analysis

J. R. Chapman

Wiley_Default, 1995

ISBN 047195831X

Mass Spectrometry for Chemists and Biochemists

Robert Alexander Walker Johnstone, M. E. Rose

Cambridge University Press, 1996

ISBN 0521424976

Introduction to Mass Spectrometry

By J. Throck Watson

Lippincott-Raven, 1997

ISBN 0397516886

Ionization Methods in Organic Mass Spectrometry

By Alison E. Ashcroft, Royal Society of Chemistry (Great Britain)

Royal Society of Chemistry, 1997

ISBN 0854045708

Accelerator Mass Spectrometry: Ultrasensitive Analysis for Global Science

Claudio Tuniz, John R. Bird, Gregory F. Herzog, David Fink

CRC Press, 1998

ISBN 0849345383

Mass Spectrometry in Biology & Medicine

By A. L. Burlingame, Steven A. Carr, Michael A. Baldwin

Humana Press, 1999

ISBN 0896037991

Mass Spectrometry and Genomic Analysis

J. Nicholas Housby

Springer, 2001

ISBN 0792371739

Mass Spectrometry Basics

Christopher G. Herbert, Robert Alexander Walker Johnstone

CRC Press, 2002

ISBN 0849313546

Liquid Chromatography Mass Spectrometry: An Introduction Robert E. Ardrey

Wiley, 2003

ISBN-10: 0471498017

Mass Spectrometry: A Textbook

J?rgen H. Gross

Springer, 2004

ISBN 3540407391

Quadrupole Ion Trap Mass Spectrometry

By Raymond E. March, John F. Todd

Wiley-IEEE, 2005

ISBN 0471717975

The Expanding Role of Mass Spectrometry in Biotechnology

Gary Siuzdak

McC Pr, 2006

ISBN 0974245127

Quantitative Applications of Mass Spectrometry

Pietro Traldi, Franco Magno, Irma Lavagnini, Roberta Seraglia

Wiley, 2006

ISBN-10: 0470025166

Assigning Structures to Ions in Mass Spectrometry

John L. Holmes, Christiane Aubry, Paul M. Mayer

CRC, 2006

ISBN-10: 0849319501

Mass Spectrometry: Principles and Applications

Edmond de Hoffmann, Vincent Stroobant

Wiley-Interscience, 2007

ISBN 047003310X

Quantitative Proteomics by Mass Spectrometry (Methods in Molecular Biology)

Salvatore Sechi

Humana Press, 2007

ISBN-10: 1588295710

Computational Methods for Mass Spectrometry Proteomics

Ingvar Eidhammer, Kristian Flikka, Lennart Martens, Svein-Ole Mikalsen

Wiley-Interscience, 2008

ISBN-10: 0470512970

Books that use resolution is Δm

Mass Spectrometry Desk Reference

David Sparkman

Global View, 2006

ISBN-10: 0966081390

Introduction to Mass Spectrometry: Instrumentation, Applications, and Strategies for Data Interpretation

J. Throck Watson, O. David Sparkman

Wiley, 2007

Language: English

ISBN-10: 0470516348

Fundamentals of Contemporary Mass

Chhabil Dass, 2007

ISBN-10: 0471682292

Proteomics in Practice: A Guide to Successful Experimental Design

Reiner Westermeier, Tom Naven, Hans-Rudolf H??pker

Wiley, 2008

ISBN-10: 3527319417