Hydrogen/deuterium exchange: Difference between revisions

Revision as of 01:39, 27 December 2005

Hydrogen/deuterium exchange
DRAFT DEFINITION
The exchange of hydrogen with deuterium in solution prior to introduction into a mass spectrometer or by reaction with a deuterated collision gas inside a mass spectrometer.
Considered between 2004 and 2006 but not included in the 2006 PAC submission
This is an unofficial draft definition presented for information and comment. Recommended terms \| Full list of terms

See additional comments on the Hydrogen/deuterium exchange discussion page (archive of discussion between 2004 and 2006)

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 {{DefName|
-A technique used for exploring the conformational structure of analyte by means of the surface accessibility with a deuterated reactant. The deuterium-labeling reaction is carried out either in the gas-phase inside a [[mass spectrometer]] or in the solution-phase prior to introduce the sample into a [[mass spectrometer]].
+The exchange of hydrogen with deuterium in solution prior to introduction into a [[mass spectrometer]] or by reaction with a deuterated [[collision gas]] inside a [[mass spectrometer]].
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