Hydrogen/deuterium exchange: Difference between revisions

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The exchange of hydrogen with deuterium in solution prior to introduction into a [[mass spectrometer]] or by reaction with a deuterated [[collision gas]] inside a [[mass spectrometer]].
|acronym=(HDX)
|def=Exchange of [[wikipedia:hydrogen|hydrogen]] atoms with [[wikipedia:deuterium|deuterium]] atoms in a chemical species in solution prior to introduction into a [[mass spectrometer]], or by [[ion/molecule reaction]] with a neutral gas inside a mass spectrometer.
|rel=
|ref=W. Blum, E. Schlumpf, J. G. Liehr, W. J. Richter. Tetrahedron Lett. 17, 565 (1976). (http://dx.doi.org/10.1016/S0040-4039(00)77911-1 )
 
S. Sethi, D. Smith, J. McCloskey. Biochem. Biophys. Res. Commun. 112, 126 (1983). (http://dx.doi.org/10.1016/0006-291X(83)91806-5 )
}}
}}
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[[Category:Reactions]]
[[Category:Reactions]]
[[Category:Isotopic labeling]]

Latest revision as of 17:54, 1 April 2024

IUPAC RECOMMENDATIONS 2013
Hydrogen/deuterium exchange (HDX)
Exchange of hydrogen atoms with deuterium atoms in a chemical species in solution prior to introduction into a mass spectrometer, or by ion/molecule reaction with a neutral gas inside a mass spectrometer.
Related Term(s):
Reference(s):

W. Blum, E. Schlumpf, J. G. Liehr, W. J. Richter. Tetrahedron Lett. 17, 565 (1976). (http://dx.doi.org/10.1016/S0040-4039(00)77911-1 )

S. Sethi, D. Smith, J. McCloskey. Biochem. Biophys. Res. Commun. 112, 126 (1983). (http://dx.doi.org/10.1016/0006-291X(83)91806-5 )

From Definitions of Terms Relating to Mass Spectrometry (IUPAC Recommendations 2013); DOI: 10.1351/PAC-REC-06-04-06 © IUPAC 2013.

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